Slide 10: BM of CML in chronic phase:

	Hypercellularity.
	The megakaryocytes maybe decreased in size but generally increased in number.
	M/E ratio was much increased, generally > 5:1
	The majority of the cells are neutrophils, metamyelocytes, and myelocytes.
	The basophil count is almost invariably increased,
	The eosinophils may also be increased.
	Monocytosis may be observed.
	While collagen fibrosis in the marrow is unusual at presentation, significant degrees of reticulin stain-measured fibrosis are noted in about half of the patients

Figure 1:

說明: BM of CML in chronic phase.

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