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Bing-Wen Soong (宋秉文)

Bing-Wen Soong(宋秉文)

簡介

學歷
  1. 國防醫學院醫學系畢業
  2. 國立陽明大學臨床醫學研究所博士
經歷 現職:
  1. - 迄今 台北榮民總醫院 周邊神經科主治醫師兼科主任
  2. - 迄今 陽明大學醫學院神經學科教授兼科主任
  3. - 迄今 台灣神經罕見疾病學會理事長
  4. - 迄今 Journal of Neurogenetics、Cerebellum and Ataxias---等雜誌副主編
經歷:
  1. - 台灣神經學學會神經基因學組首屆組長
醫療專長
  1. 神經基因遺傳及退化性疾病 (顫抖症、 舞蹈症、 小腦運動失調症、 家族性中風、 失智症、腦白質病變 ---等) 之診斷及治療
  2. 神經基因學
  3. 神經退化性疾病
  4. 神經傳導檢查暨肌電圖
  5. 分子基因病理學
  6. 肉毒桿菌注射
  7. 新治療方法之人體臨床試驗

著作

Awards:

  1. 民國106年美國臨床研究專業人員協會首席研究者在臨床研究的傑出領導獎
  2. 民國105年國家生技醫療產業策進會國家品質標章(小腦萎縮症的診療與研究)
  3. 民國104年科技部傑出研究獎
  4. 民國104年台北榮民總醫院醫師醫療創新獎第二名
  5. 民國103年台北榮民總醫院醫師學術論文獎第二名
  6. 民國102年台北榮民總醫院醫師學術論文獎第二名
  7. 民國100~108年陽明大學教師學術卓越獎勵

Focus

  1. Clinical and genetic research of neurodegenerative disorders, i.e. cerebellar ataxias, Huntington’s disease, CADASIL, Kennedy disease.
  2. Clinical trials of therapies for neurodegenerative disorders.
  3. Botulinum therapy.

Awards and Honors

  1. The “Outstanding Leadership in Clinical Research by a Principal Investigator” award granted by the Association of Clinical Research Professional, 2017.
  2. The SNQ (Symbol of National Quality) award (“Services and Research for Cerebellar Ataxias”), Institute for Biotechnology and Medicine Industry, Taiwan, 2016.
  3. Outstanding Research Award, Ministry of Science and Technology, R.O.C., 2015
  4. Medical Innovation Award (the Second Place), Taipei Veterans General Hospital, ROC, 2015.
  5. Best Research Paper Award (the second place), Taipei Veterans General Hospital, ROC, 2014.
  6. Best Research Paper Award (the second place), Taipei Veterans General Hospital, ROC, 2013.
  7. Excellence in Research Award, National Yang-Ming University, ROC, 2011-2019.

Selected Publications

  1. Soong BW, Cheng CH, Liu RS, Shan DE. Machado-Joseph disease: clinical, molecular, and metabolic characterization in Chinese kindreds. Ann Neurol 1997 April;41(4):446-52.
  2. Soong BW, Lu YC, Choo KB, Lee HY. Frequency analysis of autosomal dominant cerebellar ataxias in Taiwanese patients and clinical and molecular characterization of spinocerebellar ataxia type 6. Arch Neurol 2001 Jul:58(7):1105-9.
  3. Shan DE, Soong BW, Sun CM, Lee SJ, Liao KK, Liu RS. Spinocerebellar ataxia type 2 presenting as familial levodopa-responsive parkinsonism. Ann Neurol 2001 Dec;50(6):812-5.
  4. Chung MY, Lu YC, Cheng NC, Soong BW. A novel autosomal dominant spinocerebellar ataxia (SCA22) linked to chromosome 1p21-q23. Brain 2003 Jun;126(6):1293-9.
  5. Lin YS, Chen CM, Soong BW, Wu YR, Chen HM, Yeh WY, Wu DR, Lin YJ, Poon PWF, Wang CH, and Chern YJ. Dysregulated brain creatine kinase is associated with hearing impairment in mouse models of Huntington disease. J Clin Invest 2011 Apr;121(4):1519-23.
  6. Lee YC, Durr A, Majczenko K, Huang YH, Liu YC, Lien CC, Tsai PC, Ichikawa Y, Goto J, Monin ML, Li JZ, Chung MY, Mundwiller E, Shakkottai V, Liu TT, Tesson C, Lu YC, Brice A, Tsuji S, Burmeister M, Stevanin G, Soong BW. Mutations in KCND3 Cause Spinocerebellar Ataxia Type 22. Ann Neurol 2012 Dec 31;72(6):859-69. (Highlighted by Ellen Bible in Nature Reviews Neurology2012;8:472 entitled: “Mutations in KCND3 linked to SCAs”)
  7. Soong BW, Huang YH, Tsai PC, Huang CC, Pan HC, Lu YC, Chien HJ, Liu TT, Chang MH, Lin KP, Tu PH, Kao LS,* Lee YC.* Exome Sequencing Identifies GNB4 Mutations as a cause of Dominant Intermediate Charcot-Marie-Tooth Disease. Am J Hum Genet 2013 Mar 7;92(3):422-30.
  8. Guo YC, Lin JJ, Liao YC, Tsai PC, Lee YC, Soong BW. Spinocerebellar ataxia 35: novel mutations in TGM6 with clinical and genetic characterization. Neurology 2014 Oct 21;83(17):1554-61.
  9. Lee YC, Tsai PC, Guo YC, Hsiao CT, Liu GT, Liao YC, Soong BW.* Spinocerebellar ataxia type 36 in the Han-Chinese. Neurol Genet 2016 Apr 12;2(3):e68.
  10. Tsai YA, Liu RS, Lirng JF, Yang BH, Chang CH, Wang YC, Wu YS, Ho JHC, Lee KS, Soong BW.* Treatment of Spinocerebellar Ataxia with Mesenchymal Stem Cells: A Phase I/IIa Clinical Study. Cell Transplantation 2017 Mar 13;26(3):503-512.