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Wen-Sheng Huang (黃文盛)

  • 28757301
Wen-Sheng Huang(黃文盛)

簡介

學歷
  1. 國防醫學院
  2. 美國加州大學爾灣分校,長堤榮民醫學中心,甲狀腺實驗室進修
  3. 美國南加州大學公共衛生學院進修
  4. 美國科州橡樹嶺及德州聖安全東尼分校輻射安全人員進修
  5. 日本千葉市放射線醫學總合研究所短期專業除污訓練
  6. 中央研究院微生物免疫實驗室
經歷 現職:
  1. - 迄今 臺北榮民總醫院 核醫部暨正子中心、部主任
經歷:
  1. - 中華民國核醫學學會理事長、副理事長、常務理事、秘書長
  2. - 中華民國家庭醫學專科醫師
  3. - 三軍總醫院核子醫學部 部主任、核醫診斷科主任、核醫製藥科主任
  4. - 三軍總醫院核子醫學部、內科部 住院醫師
  5. - 彰化基督教醫院 核醫科及醫研部協同主任
  6. - 中華民國核醫學學會 專科評鑑委員會主任委員
  7. - 核醫學雜誌 總編輯、副總編輯
  8. - 彰化基督教醫院 核醫科及醫研部協同主任

著作

 

 

 

 

著作:  PUBLICATIONS:

PUBLICATIONS SINCE 2006 :

REFEREED PAPER: SCI or EI Only

1. Yeh HB, Ma KH, Chou YH, Chang CR, Huang WS. Evaluating dopamine transporter activity with Tc-99m TRODAT-1 SPECT in drug naïve Tourette’s adults. Nucl Med Comm 2006;27:779- 784. (Correspondent).

2. Chang CJ, Huang WS, Su HK, Chen JC. Separation of two radionuclides in simultaneous dual-isotope imaging with independent component analysis. Biomed Eng Appl Basis Comm 2006;18:264-269. EI

3. Shih WJ, Huang WS, Milan PP. F-18 FDG PET demonstrates crossed cerebellar diaschiasis 20 years after stroke. Clin Nucl Med 2006;31:259-61.

4. Lee JK, Liu RS, Wu SY, Huang WS, Chiu MC. Tl-201 scan in evaluating thyroid nodules following equivocal fine-needle aspiration cytology Nuklearmedizin 2006; 45:201-205. (Correspondent).

5. Chou YH, Huang WS, Su TP, et al. Dopamine transporters and cognitive dysfunction in methamphetamine abuser a short abstinence: a SPECT study. Eur J Neuropsychpharm 2007; 17:46-52. .

6. Lee JK, Liu WS, Lin YS, et al. Tl-201 SPECT predicts response to IMRT for recurrent oral SCC. Nuklearmedizin 2007; 46:169-74. (Correspondent). SCI

7. Chang CY, Lin LF, Lin YS, et al. Laryngeal giant cell tumor mimicking thyroid cancer demonstrated by PET/CY. Clin Nucl Med 2007;32:390-392.

8. Wu SY, Huang WS, Ho E, et al. Compound W, a 3,3’-diiodothyronine sulfate cross-reactive substance in serum from pregnant womenn- a potential marker for fetal thyroid function. Pediatr Res 2007;61:307-312.

9. Peng CJ, Huang YY, Huang WS, Shiue CY. An automated synthesis of N, N-dimethyl-2-2 (2- amino-4-[F18]fluorophenylthio)benzylamine(4-[F18]-ADAM) for imaging serotonin transporters.  Appl Radiat Istotopes 2007; 66: 625-631.

10. Wu SY, Huang WS, Ho E, Wu E, Fisher DA. Compound W, a 3,3'-diiodo- thyronine sulfate cross- reactive substance in serum from pregnant women--a potential marker for fetal thyroid function. Pediatr Res. 2007;61:307-12.

11. Shih WJ, Shih GL, Huang WS, Milan P. Duodenogastric reflux in a hiatal hernia seen as retrocardiac activity on 99mTc-tetrofosmin cardiac SPECT raw-data iImages. J Nucl Med Technol. 2007; 35: 252-4.

12. Chang CY, Tsai CS, Peng YJ, Huang WS. Large B-cell lymphoma mimicking ischemic heart disease demonstrated by F-18 fluorodeoxyglucose PET/CT in a heart transplant patient. J Nucl Cardiol 2007; 14: 754-7. (Correspondent).

13. Cheng CY, Huang WS, Shen DH et al. FDG PET/CT demonstrated rapid progression of mediastinal lymphadenopathy in sarcoidosis. Clin Nucl Med 2007; 32: 117-21.

14. Shih WJ, Mitchell B, Milan P, Huang WS. 2-Deoxy-2-[F-18]fluoro-D-glucose positron emission tomography illustrates two visceral tumors in a post kidney transplant patient with multiple cutaneous malignancies. Mol Imaging Biol 2007; 9: 1-5.

15. Yeh HB, Lee CS, Ma KH, Lee MS, Chang CJ, Huang WS. Phasic dysfunction of dopamine transmission in Tourette’s syndrome evaluated with 99mTc TRODAT-1 imaging. Psych Res 2007; 156: 75-82. (Correspondent).

16. Wu SY, Polk DH, Huang WS, et al. 3'-monoiodothyronine sulfate and triac sulfate are thyroid hormone metabolites in developing sheep. Pediatr Res. 2008; 63: 149-153.

17. Ma KH, Huang WS, Huang SY, Cheng CY, Chen CY, Shen LH, Liu JC, Fu YK. Imaging serotonin transporters using [123I]ADAM SPECT in a parkinsonian primate model. Appl Radiat Isot. 2008; 66:1799-803.

18. Chundru S, Wong CY, Wu D, Balon H, Palka J, Chang CY, Gaskill M, Cheng CY, Huang WS, Fink-Bennett D. Granulomatous disease: is it a nuisance or an asset during PET/computed tomography evaluation of lung cancers. Nucl Med Commun. 2008; 29: 623-7.

19. Shih G, Shih WJ, Huang WS, Milan PP. Hashimoto thyroiditis and Takayasu aortitis: visualization of the thyroid gland and ring appearance of the mediastinum on F-18-FDG PET. Clin Nucl Med. 2008; 33(5):377-9

20.Shih WJ, Shih G, Huang WS. Active bleeding in hematoma of the abdominal rectus muscle shown by Tc-99m red blood cell scintigraphy: compared with CT. Clin Nucl Med. 2008; 33(4):301-4.

21.Chang CY, Peng YJ, Shen DH, Huang WS, Cherng SC. Detection of multiple myeloma by PET/CT in a patient with colon cancer. Clin Nucl Med. 2008; 33(5):367-70

22.Li YS. Huang WS, Ma KH, et al. Comparison of singel and dual Tc-99m TRODAT-1 and I-123 IBZM brain SPECT in non-human primates. Nucl Med Biol 2009; 39: 605-11.

23.Chang CY, Cheng CY, Shen DH, Bai CY, Lin LF, Huang WS. Tumoral calcinosis demonstrated on Tc-99m sestamibi scintigraphy. Clin Nucl Med. 2008; 33(12):920-1. (Correspondent)

24. Ma KH, Lee JK, Huang SY, Yeh CB, Shen YC, Shen LH, Chen CC, Liu RS, Liu JC, Huang WS. Simultaneous [(99m)Tc]TRODAT-1 and [ (123)I]ADAM Brain SPECT in Nonhuman Primates. Mol Imaging Biol. 2009; 11: 253-62. (correspondent)

25.Ma KH, Huang WS, Kuo YY, et al. Validation of 4-[(18)F]-ADAM as a SERT imaging agent using micro-PET and autoradiography. Neuroimage. 2009;45: 687-93.

26.Liao CH, Ling Z, Chou CH, Huang WS, et al. Invovement of nigrostriatial pathway in Japanese encephalitis with movement disorder: evidence from 99mTc TRODAT-1 and I-123 IBZM imagings. Mol Imaging Biol 2009; online June, 23.

27. Wu YC, Peng GS, Cheng CA, Lin CC, Huang WS, et al. 99mTc TRODAT-1 and I-123 IBZM SPECT studies in a patient with extrapontine myelinolysis with parkinsonian features. Ann Nucl Med 2009; 23: 409-12.

28.Kuo CL, Pan RY, Wu JL, Huang WS, Wang SJ. Stress fractures of forearm bones in military recruits of rifle drill training. J Trauma. 2009; 67: 742-5.

29.Chen JC, Huang TW, Cheng YL, Chang H, Tzao C, Huang WS, Lee SC. Prognostic value of 18-FDG uptake in early stage NSCLC. Thorac Cardiovasc Surg. 2009; 57: 413-6.

30. Sung YF, Hsu YD, Huang WS. 99mTc TRODAT-1 SPECT study in evaluation of Holmes tremor after thalamic hemorrhage. Ann Nucl Med 2009; published online 20 May 2009.

31.Wong CY, Noujaim D, Fu HF, Huang WS, Cheng CY, Thie J, Dalal I, Chang CY, Nagle C. Time Sensitivity: A Parameter Reflecting Tumor Metabolic Kinetics by Variable Dual-Time F-18 FDG PET Imaging. Mol Imaging Biol. 2009 ; 11 : 283-90.

32.Huang YY, Huang WS, Chu TC, Shiue CY. An improved synthesis of 4-[(18)F]-ADAM, a potent serotonin transporter imaging agent. Appl Radiat Isot. 2009; 67: 1063-1067.

33.Chen JC, Huang TW, Cheng YL, Chang H, Tzao C, Huang WS, Lee SC. Prognostic value of 18F-FDG uptake in early stage NSCLC. Thorac Cardiov Surg 2009; 57: 413- 416.

34.Shih WJ, Shih G, Milan PP, Chang CY, Huang WS. Intrathoracic gastric activity on cholescintigraphy results in a large hiatus hernia with duodenogastric reflux. Clin Nucl Med. 2010; 35: 376-8.I

35.Huang YY, Ma KH, Tseng TW, Chou TK, Ng H, Mirsalis JC, Fu YK, Chu TC, Huang WS,  Shiue CY. Biodistribution, toxicity and radiation dosimetry studies of the serotonin transporter radioligand 4-[(18)F]-ADAM in rats and monkeys. Eur J Nucl Med Imaging 2010; 37: 545-55.

36.Chang CY, Tzao C, Lee SC, Lee JK, Chen CY, Huang WS. Incremental value of integrated FDG PET/CT in evaluating indeterminate solitary pulmonary nodule for malignancy. Mol Imaging Biol 2010; 12: 204-9. (Correspondent)

37.Li IH, Huang WS, Shiue CY, et al. Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET. Neuroimage. 2010: 49:1259-70.

38.Chen YA, Huang WS, Lin YS, et al. Characterization of 4-[18F]-ADAM as an imaging agent for SERT in non-human primate brain using PET: a dynamic study. Nucl Med Biol 2012; 39:279-85.

39.Huang TW, Hsieh CM, Chang H, Cheng YL, Tzao C, Huang WS, Lee SC. Standard uptake value of positron emission tomography in clinical stage I lung cancer: clinical application and pathological correlation. Eur J Cardiothorac Surg 2012; 41: 869-73.

40.Ho PS, Shih MC, Ma KH, Huang WS, Ho KK, Yen CH, Lu RB, Huang SY. Availability of the serotonin transporter in patients with alcohol dependence. World J Biol Psychiatry 2011; 12: 134-42.

41.Yeh CB, Huang WS, Lo MC, et al.  The rCBF brain mapping in adolescent ADHD comorbid developmental coordination disorder and its changes after MPH challenging. Eur J Paediatr Neurol. 2012 Mar 13. [Epub ahead of print]

42.Huang YY, Huang WS, Ma KS, Shiue CY. PET imaging of the brain serotonin transporters (SERT) with 4-[18F]-ADAM) and its analogs. Appl Radiat Isot. 2012;70: 2298-307. (Co-1st author).

43.Yeh HB, Ma KH, Chou YH, CY Shiue, Huang WS. Reproducibility of Tc-99m TRODAT-1 SPECT in healthy young adults. Psych Res 2012; 70: 2298-307. (Correspondent).

44.Li MH, Chen PH, Ho ST, Tung CS, Tseng CJ, Huang WS, et al. Lower Body Negative Pressure Induced Vagal reaction: Role for the Osmopressor Response? Am J Hypertens 2013 Jan; 26:5-12.

45.Kang HH, Wang CH, Chen HC, et al. Investigating the effects of noise-induced hearing loss on serotonin transporters in rat brain using 4-[(18)F]-ADAM/small animal PET. Neuroimage. 2013;75:262-9.

46.Ho PS, Ho KK, Huang WS, et al. Association study of serotonin transporter availability and SLC6A4 gene polymorphisms in patients with major depression. Psych Res 2013;212:216-22.

47.Weng SJ, Shiue CY, Huang WS, et al. PET imaging of serotonin transporters with 4-[(18)F]-ADAM in a Parkinsonian rat model. Cell Transplant. 2012 Oct 31. [Epub ahead of print]

48.Huang WS, Huang SY, Ho PS, et al. Distribution of N ,N-Dimethyl-2-(2-Amino-4-18F- Fluoro phenylthio) benzylamine (4-[18F]-ADAM) in human brain: a preliminary study. Eur J Nucl Med Mol Imaging 2013; 40:115-24.

49.Cheng CY, Su TF, Lin YH, Ho CL, Huang WS. Rare axillary metastatsis from squamous cell carcinoma of the tonsil. Clin Nucl Med 2013; 38: 495-589 (Correspondent).

50.Chen CC, Huang WS, Hung GU, Chen WC, Kao CH, Chen J. Left-ventricular dyssynchrony evaluated by Tl-201 gated SPECT myocardial perfusion imaging: a comparison with Tc-99m sestamibi. Nucl Med Commun 2013; 34: 229-32.

51.Hsu TH, Huang WS, Chen CC, et al. Left ventricular systolic and diastolic dyssynchrony assessed by phase analysis of gated SPECT myocardial perfusion imaging: a comparison with speckle tracking echocardiography. Ann Nucl Med 2013; 27:764-71.

52.Huang WY, Kao CH, Huang WS, et al. F-18 FDG PET and combined F-18 FDG –contrast CT parameters as predictors of tumor control for HCC after stereotactic ablative radiotherapy. J Nucl Med 2013; 54: 1710-6.

53.Cheng CY, Lee KW, Lee CH, et al. Time sensitivity of single pulmonary nodule: A new cancer characteristic metabolic parameter by F-18 FDG PET. Biomed Res Int 2014; 2014: 830135. Doi:10.1155/2014/830135. Epub 2014 May 18. (Correspondent).

54.Ooi H, Chen CY, Hsiao YC, Huang WS, Hsieh BT. Influence of thyroid transcrition factir-1 on FDG uptake and prognosis of NSCLC. Anticancer 2014; 34: 2467-75. (Correspondent).

55.Klein R, Hung GU, Wu DC, et al. Feasibility and operator variability of myocardial blood flow and reserve measurements with Tc-99m MIBI quantitative dynamic SPECT/CT imaging. J Nucl Cardiol 2014; 21:1075-88.

56.Hsu B, Chen FC, Wu T, et al. Quantitative of myocardial blood flow and myocardial flow reserve with Tc-99m MIBI dynamic SPECT/CT to enhance detection of CAD. Eur J Nucl Med Mol Imaging 2014; 41: 2294-306.

57.Huang WS, Huang CH, Lee CL, et al. Relation of early post-stress left ventricular dyssynchrony and the extent of angiographic coronary artery disease. J Nucl Cardiol. 2014; 21: 1048-56.

58.Chu CH, Yuan MC, Huang WS, Hsieh BT. Dosimetry and kVp standardization for quality assurance of mammography. Radiat Phys Chem 2014;104: 316–320 (Correspondent).

59.Yeh YW, Ho PS, Chen CY, Kuo SC, Liang CS, Ma KH, Shiue CY, Huang WS, et al. Incongruent reduction of serotonin transporter associated with suicide attempts in patients with major depressive disorder: a PETstudy with 4-[18F]-ADAM. Int J Neuropsychopharmacol. 2014 Oct 31;18 (3).

60.Chiu CH, Li IH, Weng SJ, Huang YS, Wu SC, Chou TK, Huang WS, et al. PET imaging of serotonin transporters with 4-[F-18]-ADAM in a Parkinsonian rat model with porcine neural xenografts. Cell Transplant. 2015 May 20. [Epub ahead of print]

61.Ko KY, Kao CH, Lin CL, Huang WS, Yen RF. 131I treatment for thyroid cancer and the risk of developing salivary and lacrimal gland dysfunction and a second primary malignancy: a nationwide population-based cohort study. Eur J Nucl Med Mol Imaging. 2015 Apr 22. [Epub ahead of print].

62.Liu CH, Huang WS, Wang HH, et al. Airway obstruction due to tracheomalacia caused by innominate artery compression and a kyphotic cervical spine. Ann Thorac Surg. 2015; 99: 685-7.

63.Yeh YW, Ho PS, Kuo SC, Chen CY, Liang CS, Yen CH, Huang CC, Ma KH, Shiue CY, Huang WS, et al. Disproportionate Reduction of Serotonin Transporter May Predict the Response and Adherence to Antidepressants in Patients with Major Depressive Disorder: A PET Study with 4-[18F]-ADAM. Int J Neuropsychopharmacol. 2015 Jan 7;18(7).

64.Lin CS, Chen SJ, Sung CC, Lin CL, Lin SH, Cheng SM, Wang IK, Huang WS, Kao CH. Hemodialysis is associated with increased peripheral artery occlusive disease risk among patients with end-stage renal disease: A nationwide population-based cohort study. Medicine (Baltimore). 2015 Jul; 94 (28):e1164. doi: 10.1097/MD.0000000000001164.

65.Sun LM, Lin CL, Liang JA, Huang WS, Kao CH. Radiotherapy did not increase thyroid cancer risk among women with breast cancer: A nationwide population-based cohort study. Int J Cancer. 2015 Jul 1. doi: 10.1002/ijc.29667. [Epub ahead of print].

66.Huang YY, Cheng CY, Huang WS, Ma KH, Tseng TW, Chou TK, Huang Y, Shiue CY.Toxicity and radiation dosimetry studies of the serotonin transporter radioligand [(18) F]AFM in rats and monkeys.EJNMMI Res. 2014 Dec;4(1):71. doi: 10.1186/s13550-014-0071-1. Epub 2014 Dec 29. (Correspondent).

67.Yeh YW, Ho PS, Chen CY, Kuo SC, Liang CS, Yen CH, Huang CC, Shiue CY, Huang WS, et al. Suicidal ideation modulates the reduction in serotonin transporter availability in male military conscripts with major depression: A 4-[18F]-ADAM PET study. World J Biol Psychiatry. 2015 Jun 12:1-11. [Epub ahead of print]

68Ko KY, Kao CH, Lin CL, Huang WS, Yen RF. (131)I treatment for thyroid cancer and the risk of developing salivary and lacrimal gland dysfunction and a second primary malignancy: a nationwide population-based cohort study. Eur J Nucl Med Mol Imaging. 2015 Jul;42(8):1172-8.

69.Tsai CJ, Cheng CY, Shen HY, Kuo SJ, Yang LH, Wang LY, Lee CH, Wang JJ, Huang WS. Tc-99m imaging in thyroidectomized differentiated thyroid cancer patients immediately before I-131 treatment. Nucl Med Communi 2015; 37: 182-7. (Correspondent). SCI

70.Lin CY, Lin CL, Huang WS, Kao CH. Risk of breast cancer in patients with thyroid cancer receiving or not receiving I-131 treatment: A nationwide population-based cohort study. J Nucl Med. 2015 Dec 30. pii: jnumed.115.164830. [Epub ahead of print]

71.Chen YG, Lin TY, Dai MS, Lin CL, Hung Y, Huang WS, Kao CH. Risk of peripheral artery disease in patients with carbon monoxide poisoning: A population-based retrospective cohort study. Medicine (Baltimore). 2015 Oct;94(40):e1608. doi: 10.1097/MD.0000000000001608.

72.Lin TY, Chen YG, Lin CL, Huang WS, Kao CH. Inflammatory Bowel Disease Increases the Risk of Peripheral Arterial Disease: A Nationwide Cohort Study. Medicine (Baltimore). 2015 Dec;94(52):e2381. doi: 10.1097/MD.0000000000002381.

73.Ko KY, Yen RF, Lin CL, Cheng MF, Huang WS, Kao CH. Pregnancy outcome after I-131 therapy for patients with thyroid cancer: A nationwide population-based cohort study. Medicine (Baltimore). 2016 Feb;95(5):e2685. doi: 10.1097/MD.0000000000002685.

74.Ooi H, Chen CY, Hsiao YC, Huang WS, Hsieh BT. Fluorodeoxyglucose uptake in advanced non-small cell lung cancer with and without pulmonary lymphangitic carcinomatosis. Anticancer Res 2016 36: 4313-20. (Correspondent)

75.Tsai CJ, Cheng CY, Shen DH, Kuo SJ, Lee CH, Chang MC, Huang WS. Tc-99m imaging in thyroidectomized differentiated thyroid cancer patients immediately before I-131 treatment. Nucl Med Commun. 2016; 37 (2): 182-7.  (Correspondent)