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杜培基 (Pei-Chi Tu)
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[Publications]
Chen, M. H., Chang, W. C., Lin, W. C.,
Tu, P. C.
, Li, C. T., Bai, Y. M., Tsai, S. J., Huang, W. S., & Su, T. P. Functional dysconnectivity of frontal cortex to striatum predicts ketamine infusion response in treatment-resistant depression. INT J NEUROPSYCHOPH. 2020; [epub ahead of print].
Chen, M. H., Hsu, J. W., Huang, K. L., Tsai, S. J., Su, T. P., Li, C. T., Lin, W. C.,
Tu, P. C.
, & Bai, Y. M. Role of obesity in systemic low-grade inflammation and cognitive function in patients with bipolar I disorder or major depressive disorder. CNS spectrums. 2020; 1-7 [epub ahead of print].
Chen, M. H., Kao, Z. K., Chang, W. C.,
Tu, P. C.,
Hsu, J. W., Huang, K. L., Su, T. P., Li, C. T., Lin, W. C., Tsai, S. J., & Bai, Y. M. Increased Proinflammatory Cytokines, Executive Dysfunction, and Reduced Gray Matter Volumes in First-Episode Bipolar Disorder and Major Depressive Disorder. J Affect Disord. 2020; 274, 825–831.
Chen, M. H., Lin, W. C.,
Tu, P. C.
, Li, C. T., Bai, Y. M., Tsai, S. J., & Su, T. P. Antidepressant and antisuicidal effects of ketamine on the functional connectivity of prefrontal cortex-related circuits in treatment-resistant depression: A double-blind, placebo-controlled, randomized, longitudinal resting fMRI study. J Affect Disord. 2020; 259:15-20.
Chen, M. H., Lin, W. C., Wu, H. J., Bai, Y. M., Li, C. T., Tsai, S. J., Hong, C. J.,
Tu, P. C.
, Cheng, C. M., & Su, T. P. Efficacy of low-dose ketamine infusion in anxious vs non-anxious depression: revisiting the Adjunctive Ketamine Study of Taiwanese Patients with Treatment-Resistant Depression. CNS spectrums. 2020; 1-6 [epub ahead of print].
Bai YM, Chen MH, Hsu JW, Huang KL,
Tu PC
, Chang WC, Su TP, Li CT, Lin WC, Tsai SJ. A comparison study of metabolic profiles, immunity, and brain gray matter volumes between patients with bipolar disorder and depressive disorder. J Neuroinflammation. 2020; 17(1):42.
Chen MH, Chen YL, Bai YM, Huang KL, Wu HJ, Hsu JW, Su TP, Tsai SJ,
Tu PC
, Li CT, Lin WC, Wu YT. Functional connectivity of specific brain networks related to social and communication dysfunction in adolescents with attention-deficit hyperactivity disorder. Psychiatry Res. 2020; 284:112785.
Li CT, Cheng CM, Chen MH, Juan CH,
Tu PC
, Bai YM, Jeng JS, Lin WC, Tsai SJ, Su TP. Antidepressant Efficacy of Prolonged Intermittent Theta Burst Stimulation Monotherapy for Recurrent Depression and Comparison of Methods for Coil Positioning: A Randomized, Double-Blind, Sham-Controlled Study. Biol Psychiatry. 2020; 87(5):443-450.
PC Tu
, TP Su, WC Lin, WC Chang, YM Bai, CT Li, FH Lin. Reduced synchronized brain activity in schizophrenia during viewing of comedy movies. Scientific reports. 2019; 9(1):12738.
Tu, P. C.
, Bai, Y. M., Li, C. T., Chen, M. H., Lin, W. C., Chang, W. C., & Su, T. P. Identification of Common Thalamocortical Dysconnectivity in Four Major Psychiatric Disorders. Schizophr Bull. 2019; 45(5):1143-1151.
Chen MH, Chang WC, Bai YM, Huang KL,
Tu PC
, Su TP et al. Cortico-thalamic dysconnection in early-stage schizophrenia: a functional connectivity magnetic resonance imaging study. European archives of psychiatry and clinical neuroscience 2019; 245:8-15.
Chen, M. H., Chang, W. C., Hsu, J. W., Huang, K. L.,
Tu, P. C.*
, Su, T. P., . . . Bai, Y. M. Correlation of proinflammatory cytokines levels and reduced gray matter volumes between patients with bipolar disorder and unipolar depression. J Affect Disord, 2018; 245, 8-15. doi: 10.1016/j.jad.2018.10.106
Chen, M. H., Li, C. T., Lin, W. C., Hong, C. J.,
Tu, P. C.
, Bai, Y. M., . . . Su, T. P. Persistent antidepressant effect of low-dose ketamine and activation in the supplementary motor area and anterior cingulate cortex in treatment-resistant depression: A randomized control study. J Affect Disord, 2018; 225, 709-714. doi: 10.1016/j.jad.2017.09.008
Tu, P. C.
, Kuan, Y.H., Li, C.T., Su, T. P. Structural Correlates of Trait Impulsivity in Patients with Bipolar Disorder and Healthy Controls - A Surface-Based Morphometry Study. Psychological medicine. 2017; 47(7):1292-1299.
Tu PC
, Li CT, Lin WC, Chen MH, Su TP, Bai YM. Structural and functional correlates of serum soluble IL-6 receptor level in patients with bipolar disorder. Journal of affective disorders. 2017; 219:172-7.
Tu PC
, Kuan YH, Li CT, Su TP. Structural correlates of creative thinking in patients with bipolar disorder and healthy controls-a voxel-based morphometry study. Journal of affective disorders. 2017; 215:218-24.
Su TP, Chen MH, Li CT, Lin WC, Hong CJ, Gueorguieva R,
Tu PC
, Bai YM, Cheng CM, Krystal JH. Dose-Related Effects of Adjunctive Ketamine in Taiwanese Patients with Treatment-Resistant Depression. Neuropsychopharmacology. 2017;43(13): 2482-2492.
Lin, C.-J., Chang, F.-C., Chou, K.-H.,
Tu, P.-C.
, Lee, Y.-H., Lin, C.-P., Wang, P.-N., Lee, I.-H. Intervention versus Aggressive Medical Therapy for Cognition in Severe Asymptomatic Carotid Stenosis. American Journal of Neuroradiology. 2016; 37: 1889-1897.
Li CT, Hsieh JC, Huang HH, Chen MH, Juan CH,
Tu PC
, Lee YC, Wang SJ, Cheng CM, Su TP. Cognition-Modulated Frontal Activity in Prediction and Augmentation of Antidepressant Efficacy: A Randomized Controlled Pilot Study. Cerebral Cortex. 2016; 26(1):202-10.
Li CT, Chen MH, Lin WC, Hong CJ, Yang BH, Liu RS,
Tu PC
, Su TP. The effects of low-dose ketamine on the prefrontal cortex and amygdala in treatment-resistant depression: A randomized controlled study. Human Brain Mapping. 2016; 37(3):1080-90.
Bai, Y.M., Li, C.T., Tsai, S.J.,
Tu, P.C.
, Chen, M.H., Su, T.P. Metabolic syndrome and adverse clinical outcomes in patients with bipolar disorder. BMC psychiatry. 2016; 16(1): 488.
Tu, P. C.
, Hsu, J. W., Lan, C. C., Liu, C. C., Su, T. P., & Chen, Y. S. (2016). Structural and functional correlates of a quantitative autistic trait measured using the social responsive scale in neurotypical male adolescents. Autism Res 9(5):570-8. doi: 10.1002/aur.1535 (SCI)
Tu, P.-C.
, Lee, Y.-C., Chen, Y.-S., Hsu, J.-W., Li, C.-T., Su, T.-P., 2015. Network-specific cortico-thalamic dysconnection in schizophrenia revealed by intrinsic functional connectivity analyses. Schizophr Res 166, 137-143. (SCI)
Bai, Y.M., Su, T.P., Li, C.T., Tsai, S.J., Chen, M.H.,
Tu, P.C.
, Chiou, W.F., 2015. Comparison of pro-inflammatory cytokines among patients with bipolar disorder and unipolar depression and normal controls. Bipolar Disord 17, 269-277. (SCI)
Tu, P.C.
, Su, T.P., Huang, C.C., Yang, A.C., Yeh, H.L., Hong, C.J., Liou, Y.J., Liu, M.E., Lin, C.P., Tsai, S.J., 2014. Interleukin-1 beta C-511T polymorphism modulates functional connectivity of anterior midcingulate cortex in non-demented elderly Han males. Brain Struct Funct 219, 61-69. (SCI)
Bai, Y.M., Su, T.P., Tsai, S.J., Wen-Fei, C., Li, C.T.,
Pei-Chi, Tu
., Mu-Hong, C., 2014. Comparison of inflammatory cytokine levels among type I/type II and manic/hypomanic/euthymic/depressive states of bipolar disorder. J Affect Disord 166, 187-192. (SCI)
Li, C.T., Bai, Y.M., Hsieh, J.C., Lee, H.C., Yang, B.H., Chen, M.H., Lin, W.C., Tsai, C.F.,
Tu, P.C.
, Wang, S.J., Su, T.P., 2015a. Peripheral and central glucose utilizations modulated by mitochondrial DNA 10398A in bipolar disorder. Psychoneuroendocrinology 55, 72-80. (SCI)
Li, C.T., Su, T.P., Wang, S.J.,
Tu, P.C.
, Hsieh, J.C., 2015b. Prefrontal glucose metabolism in medication-resistant major depression. Br J Psychiatry 206, 316-323. (SCI)
Li, C.-T., Hsieh, J.-C., Huang, H.-H., Chen, M.-H., Juan, C.-H.,
Tu, P.-C.
, Lee, Y.-C., Wang, S.-J., Cheng, C.-M., Su, T.-P., 2014a. Cognition-Modulated Frontal Activity in Prediction and Augmentation of Antidepressant Efficacy: A Randomized Controlled Pilot Study. Cerebral Cortex. (SCI)
Li, C.T., Bai, Y.M., Lee, Y.C., Mao, W.C., Chen, M.H.,
Tu, P.C.
, Chen, Y.S., Chen, T.J., Chang, W.H., Su, T.P., 2014b. High dosage of hypnotics predicts subsequent sleep-related breathing disorders and is associated with worse outcomes for depression. Sleep 37, 803-809, 809a-809b. (SCI)
Li, C.T., Chen, M.H., Juan, C.H., Huang, H.H., Chen, L.F., Hsieh, J.C.,
Tu, P.C.
, Bai, Y.M., Tsai, S.J., Lee, Y.C., Su, T.P., 2014c. Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 137, 2088-2098. (SCI)
Li, C.T., Hsieh, J.C., Huang, H.H., Chen, M.H., Juan, C.H.,
Tu, P.C.
, Lee, Y.C., Wang, S.J., Cheng, C.M., Su, T.P., 2014d. Cognition-Modulated Frontal Activity in Prediction and Augmentation of Antidepressant Efficacy: A Randomized Controlled Pilot Study. Cereb Cortex. (SCI)
Chen, Y.L.,
Tu, P.C
., Lee, Y.C., Chen, Y.S., Li, C.T., Su, T.P., 2013. Resting-state fMRI mapping of cerebellar functional dysconnections involving multiple large-scale networks in patients with schizophrenia. Schizophr Res 149, 26-34. (SCI)
Ku, H.L., Lin, C.S., Chao, H.T.,
Tu, P.C.
, Li, C.T., Cheng, C.M., Su, T.P., Lee, Y.C., Hsieh, J.C., 2013. Brain signature characterizing the body-brain-mind axis of transsexuals. PLoS One 8, e70808. (SCI)
Li, C.T., Bai, Y.M.,
Tu, P.C.
, Lee, Y.C., Huang, Y.L., Chen, T.J., Chang, W.H., Su, T.P., 2012. Major depressive disorder and stroke risks: a 9-year follow-up population-based, matched cohort study. PLoS One 7, e46818. (SCI)
Tu, P.C.
, Lee, Y.C., Chen, Y.S., Li, C.T., Su, T.P., 2013. Schizophrenia and the brain's control network: aberrant within- and between-network connectivity of the frontoparietal network in schizophrenia. Schizophr Res 147, 339-347. (SCI)
Li, C.T., Chen, L.F.,
Tu, P.C.
, Wang, S.J., Chen, M.H., Su, T.P., Hsieh, J.C., 2013. Impaired prefronto-thalamic functional connectivity as a key feature of treatment-resistant depression: a combined MEG, PET and rTMS study. PLoS One 8, e70089. (SCI)
Lin, C.J.,
Tu, P.C.
, Chern, C.M., Hsiao, F.J., Chang, F.C., Cheng, H.L., Tang, C.W., Lee, Y.C., Chen, W.T., Lee, I.H., 2014a. Connectivity features for identifying cognitive impairment in presymptomatic carotid stenosis. PLoS One 9, e85441. (SCI)
Lin, C.S., Ku, H.L., Chao, H.T.,
Tu, P.C.
, Li, C.T., Cheng, C.M., Su, T.P., Lee, Y.C., Hsieh, J.C., 2014b. Neural network of body representation differs between transsexuals and cissexuals. PLoS One 9, e85914. (SCI)
Yang, A.C., Huang, C.C., Yeh, H.L., Liu, M.E., Hong, C.J.,
Tu, P.C.
, Chen, J.F., Huang, N.E., Peng, C.K., Lin, C.P., Tsai, S.J., 2013. Complexity of spontaneous BOLD activity in default mode network is correlated with cognitive function in normal male elderly: a multiscale entropy analysis. Neurobiol Aging 34, 428-438.
Liu, M.E., Huang, C.C., Chen, M.H., Yang, A.C.,
Tu, P.C.
, Yeh, H.L., Hong, C.J., Chen, J.F., Hwang, J.P., Lin, C.P., Tsai, S.J., 2014a. Effect of the BDNF Val66Met polymorphism on regional gray matter volumes and cognitive function in the Chinese population. Neuromolecular Med 16, 127-136. (SCI)
Liu, M.E., Huang, C.C., Hwang, J.P., Yang, A.C.,
Tu, P.C.
, Yeh, H.L., Hong, C.J., Liou, Y.J., Chen, J.F., Lin, C.P., Tsai, S.J., 2013a. Effect of Bcl-2 rs956572 SNP on regional gray matter volumes and cognitive function in elderly males without dementia. Age (Dordr) 35, 343-352. (SCI)
Liu, M.E., Huang, C.C., Yang, A.C.,
Tu, P.C.
, Yeh, H.L., Hong, C.J., Chen, J.F., Liou, Y.J., Lin, C.P., Tsai, S.J., 2013b. Effect of Bcl-2 rs956572 polymorphism on age-related gray matter volume changes. PLoS One 8, e56663. (SCI)
Liu, M.E., Huang, C.C., Yang, A.C.,
Tu, P.C.
, Yeh, H.L., Hong, C.J., Liou, Y.J., Chen, J.F., Chou, K.H., Lin, C.P., Tsai, S.J., 2014b. Catechol-O-methyltransferase Val158Met polymorphism on the relationship between white matter hyperintensity and cognition in healthy people. PLoS One 9, e88749. (SCI)
Liu, T.Y., Hsieh, J.C., Chen, Y.S.,
Tu, P.C.
, Su, T.P., Chen, L.F., 2012. Different patterns of abnormal gamma oscillatory activity in unipolar and bipolar disorder patients during an implicit emotion task. Neuropsychologia 50, 1514-1520. (SCI)
Teng, S., Lu, C.F., Wang, P.S., Hung, C.I., Li, C.T.,
Tu, P.C.
, Su, T.P., Wu, Y.T., 2013. Classification of bipolar disorder using basal-ganglia-related functional connectivity in the resting state. Conf Proc IEEE Eng Med Biol Soc 2013, 1057-1060. (SCI)
Tu, P.C.
, Chen, L.F., Hsieh, J.C., Bai, Y.M., Li, C.T., Su, T.P., 2012a. Regional cortical thinning in patients with major depressive disorder: a surface-based morphometry study. Psychiatry Res 202, 206-213. (SCI)
Cheng, H.L., Lin, C.J., Soong, B.W., Wang, P.N., Chang, F.C., Wu, Y.T., Chou, K.H., Lin, C.P.,
Tu, P.C.*
, Lee, I.H., 2012. Impairments in cognitive function and brain connectivity in severe asymptomatic carotid stenosis. Stroke 43, 2567-2573. (SCI)
Tu, P.C.
, Hsieh, J.C., Li, C.T., Bai, Y.M., Su, T.P., 2012. Cortico-striatal disconnection within the cingulo-opercular network in schizophrenia revealed by intrinsic functional connectivity analysis: A resting fMRI study. Neuroimage 59, 238-247.(SCI)
Tu PC
, Hsieh JC, Chen LF, Li CT, Bai YM, Su TP. Regional cortical thinning in patients with major depressive disorder: a surface-based morphometry study. Psychiatry Research, NeuroImaging(SCI)
Tu P
, R. L. Buckner , L. Zollei, K. A. Dyckman, D. C. Goff, D. S. Manoach. 2010 Feb; Reduced functional connectivity in a right-hemisphere network for spatial attention and volitional ocular motor control in schizophrenia. Brain. 133 :625-37. (SCI)
Kong J,
Tu PC*
, Z. Carolyn, Su TP. 2010 Aug Intrinsic functional connectivity of the periaqueductal gray, a resting fMRI study. Behav Brain Res. 25;211(2):215-9. 27
*co- first author
( SCI)
Krienen FM
,
Tu PC
,
Buckner RL
. 2010 Oct. Clan mentality: evidence that the medial prefrontal cortex responds to close others.
J Neurosci.
13;30(41):13906-15.(SCI)
Chen SS,
Tu PC,
Su TP, Hsieh JC, Lin YC, Chen LF. 2008 Nov. Impaired frontal synchronization of spontaneous magnetoencephalographic activity in patients with bipolar disorder. Neurosci Lett. 14;445(2):174-8.(SCI)
Tu PC,
Yang TH
,
Kuo WJ
,
Hsieh JC
Su TP. Neural correlates of antisaccade deficits in schizophrenia, an fMRI study. J Psychiatr Res .2006 Oct; 40(7):606-12. (SCI)