The features of Division of Retina:
7 staffs, including 1 professor, 2 associate professors, and 1 assistant professor.
4 with phD degree.
Major surgical services, including:
- Emergent Retinal detachment surgery, usually completed within 2 days.
- Vitreous hemorrhage surgery
- Tumor surgery
- Epiretinal membrane surgery
- Macular hole surgery, also with amniotic membrane
- Intravitreous injection of various kinds of anti-VEGF and steroid to treat age-related macular degeneration, diabetic macular edema, and retinal vein occlusion, including Lucentis, Eylea, Beovu, Vabysmo, and Ozurdex
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Retinal detachment (Pre-operative ultra wide-filed fundus image) |
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Retinal detachment (Post-operative ultra wide-filed fundus image) |
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Choroidal neovascularization visualized under optical coherence tomography angiography |
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Optical coherence tomography angiography of a patient with choroidal neovascularization treated with intravitreous anti-VEGF therapy. |
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Major medical services, including:
- Uveitis diagnosis and treatment
- Chorioretinopathy diagnosis and treatment
- Retina dystrophy diagnosis and treatment
- Genome diagnosis of retinal dystrophy
Major research categories, including:
- Stem cells therapy (iPS) for retinal dystrophy and macular degeneration
- Retinal prosthesis for retinal dystrophy and macular degeneration
- Artificial intelligence of chorioretinal disease diagnosis and prognosis
Meet Our Retina Team:
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VitreoRetina |
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Shih-Jen Chen (Chairperson) De-Kuang Huang (Uveitis Specialist) |
Ongoing Clinical trials:
1. No. CRTH258A2303E1 IRB# 2021-02-026BU
A 56-week phase IIIb/IV, open-label, one-arm extension study to assess the efficacy and safety of brolucizumab 6 mg in a Treat-to-Control regimen with maximum treatment intervals up to 20 weeks for the treatment of patients with neovascular age-related macular degeneration who have completed the CRTH258A2303 (TALON) study
2. No.GR41987 IRB# 2020-11-011BU
A multicenter, open-label extension study to evaluate the long-term safety and tolerability of faricimab in patients with diabetic macular edema.
3. No.GR42691 IRB#: 2021-03-006BU
A multicenter, open-label extension study to evaluate the long-term safety and tolerability of faricimab in patients with neovascular age-related macular degeneration (Avonelle-X)
4. No. GR41986 Balaton IRB#: 2020-07-014AU
A phase III, multicenter, randomized, double-masked, active comparator-controlled study to evaluate the efficacy and safety of faricimab in patients with macular edema secondary to central retinal or hemiretinal vein occlusion
5.No. GR41986 COMINO IRB#:2020-07-013AU
A phase III, multicenter, randomized, double-masked, active comparator-controlled study to evaluate the efficacy and safety of faricimab in patients with macular edema secondary to central retinal or hemiretinal vein occlusion
6.No.:OPT-302-1005 IRB#:2021-09-003AU
A Phase 3, Multicentre, Double-masked, Randomised Study to Evaluate the Efficacy and Safety of Intravitreal OPT-302 in Combination with Aflibercept, Compared with Aflibercept Alone, in Participants with Neovascular Age-related Macular Degeneration (nAMD).
7.No. :WR42221 IRB#:2021-09-010BU
A phase IIIb, global, multicenter, randomized, visual assessor-masked study of the efficacy, safety, and pharmacokinetics of a 36-week refill regimen for the port delivery system with ranibizumab in patients with neovascular age-related macular degeneration (velodrome)
8.No.:GR40549PORTAL IRB#:2021-09-011BU
A multicenter, open-label extension study to evaluate the long-term safety and tolerability of the port delivery system with ranibizumab in patients with neovascular age-related macular degeneration (portal)
9.No.:MR43808 SALWEEN IRB#:2022-07-022CU
A phase IIIb/IV, multicenter, open-label, single-arm study to investigate the efficacy and safety of faricimab (ro6867461) in patients with polypoidal choroidal vasculopathy
10. GR44277 Meerkat IRB#:2022-11-011BU
A phase III, multicenter, randomized, double‑masked, sham‑controlled study to investigate the efficacy, safety, pharmacokinetics, and pharmacodynamics of o7200220 administered intravitreally in patients with uveitic macular edema
Pubilcation:
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Retina |
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Shih-Jen Chen |
One-year outcomes of the treat-and-extend regimen using aflibercept for the treatment of diabetic macular . J Chin Med Assoc. |
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Shih-Jen Chen |
Factors related to unfavorable visual outcome after idiopathic epiretinal membrane surgery in patients with glaucoma. Retina. |
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Shih-Jen Chen |
Management of diabetic macular edema: experts’ consensus in Taiwan. Japanese Journal of Ophthalmology |
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Shih-Jen Chen |
Flow signal change in polyps after antivascular endothelial growth factor therapy. PLOS ONE |
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Shih-Jen Chen |
Parafoveal atrophy after human amniotic membrane graft for macular hole in patients with high myopia British Journal of Ophthalmology |
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Shih-Jen Chen |
Comparison between cryopreserved and dehydrated human amniotic membrane graft in treating challenging cases with macular hole and macular hole retinal detachment. Journal of Ophthalmology |
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Shih-Jen Chen |
Image quality and diagnostic accuracy of a Hand-held nonmydriatic fundus camera: feasibility of a telemedical approach in screening retinal diseases. Journal of the Chinese Medical Association |
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Po-Kang Lin |
PADAr: physician-oriented artificial intelligence-facilitating diagnosis aid for retinal diseases. J Med Imaging. |
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Po-Kang Lin |
The association of aldosterone with papillophlebitis and retinal artery occlusion: A case report. European Journal of Ophthalmology |
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Tai-Chi Lin |
Therapeutic effect of simultaneous intravitreal dexamethasone and aflibercept on diabetic macular edema. Acta Diabetol |
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Tai-Chi Lin |
Clinical manifestation and current therapeutics in X-juvenile retinoschisis. J Chin Med Assoc. |
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Tai-Chi Lin |
Three-Year Outcomes of Intravitreal Aflibercept Injections for Retinal Angiomatous Proliferation According to Disease Stage. Ophthalmol Ther. |
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Tai-Chi Lin |
Correlations between Clinical and Histopathologic Characteristics in Idiopathic Epiretinal Membrane. Ophthalmology. |
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Tai-Chi Lin |
Yang HY, Ko YC, Kuang TM, Chang CJ, Lin TC. Pseudophakic pupillary block after phacoemulsification and posterior chamber intraocular lens implantation: Cause identification and treatment refinement. Photodiagnosis Photodyn Ther. |
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De-Kuang Hwang |
Pluripotent Stem Cells in Clinical Cell Transplantation: Focusing on Induced Pluripotent Stem Cell-Derived RPE Cell Therapy in Age-Related Macular Degeneration. Int J Mol Sci. |
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De-Kuang Hwang |
Temporal fluctuations of cardiovascular parameters after intravitreal injections. Journal of the Chinese Medical Association |
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De-Kuang Hwang |
Deep learning to infer visual acuity from optical coherence tomography in diabetic macular edema. Front Med (Lausanne). |
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De-Kuang Hwang |
Step-wise diagnostic approach for patients with uveitis - Experts consensus in Taiwan. J Microbiol Immunol Infect. |
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De-Kuang Hwang |
Three-Year Outcomes of Patients with Neovascular Age-Related Macular Degeneration Treated with Aflibercept under the National Health Insurance Program in Taiwan. Journal of Ophthalmology |
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Tai-Chi Lin |
A simple New Technique to Peel Epiretinal Membrane Without Removing Silicone Oil. Retina |
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De-Kuang Hwang |
Optical Coherence Tomography-based Diabetic Macula Edema Screening with Artificial Intelligence. Journal of the Chinese Medical Association |
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Yu-Bai Chou |
Deep learning and ensemble stacking technique for differentiating polypoidal choroidal vasculopathy from neovascular age-related macular degeneration. Scientific Reports |
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De-Kuang Hwang |
Changes in the Systemic Expression of Sirtuin-1 and Oxidative Stress after Intravitreal Anti-Vascular Endothelial Growth Factor in Patients with Retinal Vein Occlusion. Biomolecules |
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De-Kuang Hwang |
The Era of AI-based Individualized Telemedicine is Coming. Journal of the Chinese Medical Association |
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De-Kuang Hwang |
An update on the diagnosis and management of ocular sarcoidosis. Current Opinion in Ophthalmology. |
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Yu-Bai Chou |
Retinal Microvascular Changes in Mild Cognitive Impairment and Alzheimer‘s Disease: A Systematic Review, Meta-Analysis. Front Aging Neurosci. |
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Yu-Bai Chou |
Prediction of treatment outcome in neovascular age-related macular degeneration using a novel convolutional neural network. Sci Rep. |
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Yu-Bai Chou |
Refractive status, biometric components, and functional outcomes of patients with threshold retinopathy of prematurity: systemic review and a 17-year longitudinal study. Graefes Arch Clin Exp Ophthalmol. |
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