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黃惠君 (Hui-Chun Huang)
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First Appointment
[Profile]
[Publications]
Huang CJ, Hsu SJ, Hsu YC, Chen LK, Li C,
Huang HC (corresponding author)
, Lee YH. Synthesis, characterization, and biological verification of asialoglycoprotein receptor-targeted lipopolysaccharide- encapsulated PLGA nanoparticles for the establishment of a liver fibrosis animal model. Biomater Sci 2023;11:6650-62.
Huang HC
, Chang CC, Pun CK, Tsai MH, Chuang CL, Hsu SJ, Huang YH, Hou MC, Lee FY. α-Adrenergic blockade prevented environmental temperature reduction-induced transient portal pressure surge in cirrhotic and portal hypertensive rats. Clin Sci (Lond) 2022;136:1449-66.
Huang HC
, Hsu SJ, Chang CC, Chuang CL, Hou MC, Lee FY. Effects of PCSK-9 Inhibition by Alirocumab Treatments on Biliary Cirrhotic Rats. Int J Mol Sci 2022;23:7378.
Huang HC
, Tsai MH, Chang CC, Pun CK, Huang YH, Hou MC, Lee FY, Hsu SJ. Microbiota transplants from feces or gut content attenuated portal hypertension and portosystemic collaterals in cirrhotic rats. Clin Sci (Lond) 2021;135:2709-28.
Pun CK,
Huang HC (equal contribution)
, Chang CC, Chuang CL, Yen CH,
Hsu SJ
, Lee FY, Hou MC, Huang YH. Glycyrrhizin Attenuates Portal Hypertension and Collateral Shunting via Inhibition of Extrahepatic Angiogenesis in Cirrhotic Rats. Int J Mol Sci 2021;22:7662.
Huang HC
, Ho HL, Chang CC, Chuang CL, Pun CK, Lee FY, Huang YH, Hou MC, Hsu SJ. Matrix metalloproteinase-9 inhibition or deletion attenuates portal hypertension in rodents. J Cell Mol Med 2021;25:10073-87.
Hsin IF,
Huang HC (equal contribution)
, Chang CC, Hsu SJ, Lee FY, Huo TI, Chuang CL, Hou MC, Lee SD. Insulin reverses major portal hypertension-related derangements in rats with liver cirrhosis and diabetes. Clin Sci (Lond) 2018;132:2391-405.
Hsu SJ, Tsai MH, Chang CC, Hsieh YH,
Huang HC (corresponding author)
, Lee FY, Chuang CL, Hou MC, Lee SD.
Extrahepatic angiogenesis hinders recovery of portal hypertension and collaterals in rats with cirrhosis resolution.
Clin Sci (Lond). 2018132(6):669-683.
Tsai MH,
Huang HC (equal contribution)
, Peng YS, Chen YC, Tian YC, Yang CW, Lien JM, Fang JT, Wu CS, Hsieh SY, Lee FY. Dehydroepiandrosterone Sulphate and Dehydroepiandrosterone Sul-phate/Cortisol Ratio in Cirrhotic Patients with Septic Shock: another sign of hepatoadrenal syndrome? Cric Care 2017;21:214.
Tung HC, Hsu SJ, Tsai MH, Lin TY, Hsin IF, Huo TI, Lee FY,
Huang HC (corresponding author)
, Ho HL, Lin HC, Lee SD. Homocysteine deteriorates intrahepatic derangement and portal-systemic collaterals in cirrhotic rats. Clin Sci (Lond) 2017;131:69-86.
Hsu SJ, Lee FY, Wang SS, Hsin IF, Lin TY,
Huang HC(corresponding author)
, Chang CC, Chuang CL, Ho HL, Lin HC, Lee SD. Caffeine ameliorates hemodynamic derangements and portosystemic collaterals in cirrhotic rats. Hepatology 2015;61:1672-84.
Chang CC, Wang SS, Hsieh HG, Lee WS, Chuang CL, Lin HC, Lee FY, Lee SD,
Huang HC (corresponding author)
. Rosuvastatin improves hepatopulmonary syndrome through inhibition of inflammatory angiogenesis of lung. Clin Sci (Lond) 2015;129:449-60.
Lee JY, Huo TI, Wang SS,
Huang HC (corresponding author)
, Lee FY, Lin HC, Chuang CL, Lee SD.
Diabetes enhances the intrahepatic vascular response to endothelin-1 in cirrhotic rats: association with the ETA receptor and pERK up-regulation.
Liver Int 2015;35:704-12.
Tsai MH,
Huang HC (equal contribution)
, Peng YS, Chen YC, Tian YC, Yang CW, Lien JM, Fang JT, Wu CS, Lee FY. Critical Illness-Related Corticosteroid Insufficiency in Cirrhotic Patients With Acute Gastroesophageal Variceal Bleeding: Risk Factors and Association With Outcome. Crit Care Med 2014;42:2546-55.
Hsu SJ, Wang SS, Hsin IF, Lee FY,
Huang HC (corresponding author)
, Huo TI, Lee WS, Lin HC, Lee SD. Green tea polyphenol decreases the severity of portosystemic collaterals and mesenteric angiogenesis in rats with liver cirrhosis. Clin Sci (Lond) 2014;126:633-44.
Huang HC
, Wang SS, Hsin IF, Chang CC, Lee FY, Lin HC, Chuang CL, Lee JY, Hsieh HG, Lee SD. Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats. Hepatology 2012;56:248-58.
Huang HC
, Haq O, Utsumi T, Sethasine S, Abraldes JG, Groszmann RJ, Iwakiri Y. Intestinal and plasma VEGF levels in cirrhosis: the role of portal pressure. J Cell Mol Med 2012;16:1125-33.
Lee JY, Huo TI,
Huang HC (corresponding author)
, Lee FY, Lin HC, Chuang CL, Chang CC, Wang SS, Lee SD. Propranolol modulates the collateral vascular responsiveness to vasopressin via Gα-mediated pathway in portal hypertensive rats. Clin Sci (Lond) 2011;121:545-54.
Zhang D, Utsumi T,
Huang HC
, Gao L, Sangwung P, Chung C, Shibao K, Okamoto K, Yamaguchi K, Groszmann RJ, Jozsef L, Hao A, Sessa WC, Iwakiri Y. Reticulon 4B (Nogo-B) is a novel regulator of hepatic fibrosis. Hepatology 2011; 53:1306-15.
Huang HC
, Wang SS, Chan CC, Lee FY, Chang FY, Lin HC, Hou MC, Tai CC, Lai IN, Lee SD. Chronic inhibition of nitric oxide increases the collateral vascular responsiveness to vasopressin in portal hypertensive rats. J Hepatol 2004;40:234-8.
Huang HC
, Lee FY, Chan CC, Chang FY, Wang SS, Lin HC, Hou MC, Chen CT, Tai CC, Lai IN, Lee SD. Effects of somatostatin and octreotide on portal-systemic collaterals in portal hypertensive rats. J Hepatol 2002;36:163-8.