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各項成果

六癌研究成果論文

項目指標 口腔癌團隊項目指標 大腸直腸癌團隊項目指標 肝癌團隊項目指標 肺癌團隊項目指標 乳癌團隊項目指標 子宮頸癌團隊

口腔癌多專科醫療團隊 (日曆小圖示 2005年日曆小圖示 2006年日曆小圖示 2007年

項目指標  2005年


作者

論文

期刊

于恩浩, 吳政憲, 羅文良, 高壽延, 張哲壽

前哨淋巴結切片在治療頭頸部癌症所扮演的角色.

中華牙醫學會訊: 32-34, 2005一、二月號.

Wu CW, Hung KF, Yeung TC, Kao SY

A method using vestibulo-sulcoplasty simultaneously combining spilt-thickness skin graft and palatal keratinized mucosa graft for rehabilitation of peri-implant tissue in the severely atrophic edentulous ridge secondary to oral cancer surgery

J Oral Implantol 31 (4): 186-191, 2005

Kao SY, Wu JH, Chang CS, and Chao SY*

The Synopsis of Staging, Diagnosis and Treatment Modality of Oral Cancer

J Dent. Sci. 25:159-164, 2005

Chou SJ, Kao SY, Chang CS

Spindle cell carcinoma- case report

J Dent. Sci. 25: 165-170, 2005.

Lin SC, Chang MF, Chung MY, Chang CS, Kao SY, Liu CJ, Chang KW

Frequent misrosatellite alterations of chromosome locus 4q13.1 in oral squamous cell carcinomas.

J Oral Pathol Med. 34(4):209-13, 2005.

Lin SC, Liu CJ, Ko SY, Chang HC, Liu TY, Chang KW*

Copy number amplification of 3q26-27 oncogenes in microdissected oral squamous cell carcinoma and oral brushed samples from areca chewers

J Pathol 206: 417–22

Lin SC, Lee SY, Wu YS, Lin CY, Chang CS, Chang KW*

Areca (betel) nut extract activates mitogen-activated protein kinases and NF-κB in an oral keratinocyte

Int. J Cancer 116: 526-35

Liu CJ, Lee YJ, Shin YN, Liu HF, Shieh TM, Chang KW*

Association of GST genotypes with age of onset and lymph node metastasis in oral squamous cell carcinomas

Lin SC, Chang MF, Chung MY, Kao SY, Liu CJ, Chang KW*

Frequent microsatellite alterations of chromosome locus 4q13.1 in oral squamous cell carcinomas

J Oral Pathol Med 34: 209-13

Chang JT, Wang HM, Chang KW, Chen WH, Wen MC, Hsu YM, Yung BY, Chen IH, Liao CT, Hsieh LL, Cheng AJ*

Identification of differentially expressed genes in oral squamous cell carcinoma (OSCC): overexpression of NPM, CDK1 and NDRG1 and underexpression of CHES1

Int J Cancer 114: 942-9

Liu CJ, Wong YK, Chang KW, Chang HC, Liu HF, Lee YJ*

Tumor necrosis factor-alpha promoter polymorphism is associated with susceptibility to oral squamous cell carcinoma

J Oral Pathol Med 34: 608-12

Lee YT, Don MJ, Hung PS, Shen YC, Lo YS, Chang KW, Chen CF, Ho LK

Cytotoxicity of phenolic acid phenethyl esters on oral cancer cells

Cancer Letters 223: 19-25

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項目指標  2006年


作者

論文

期刊

Kroep JR. Peters GJ. van Moorsel CJ. Catik A. Vermorken JB. Pinedo HM. van Groeningen CJ.

A trial of gemcitabine (gems) in combination with cisplatin for treatment of recurrent/metastatic head and neck squamous cell carcinoma (HNSCC).

Clin Cancer Res 2006; 12: 507-515

Tu HF, Liu CJ, Chang CS, Lui MT, Kao SY, Chang CP, Liu TY

The functional (-1171 5A → 6A) polymorphisms of matrix metalloproteinase 3 gene as a risk factor for oral submucous fibrosis among male areca users

J Oral Pathol Med. 35: 99-103, 2006

Yu EH, Lui MT, Chou SJ, Wang SJ, Hung KF, Lo WL, Chang CS, Wu

Comparison of Positron Emission Tomography and Computed Tomography for the Detection of Cervical Lymph Node Metastases of Oral Squamous Cell Carcinoma

Asian J Oral Maxillofacial Surg. 18: 109-115, 2006.

Hung KF, Chang CS, Liu CJ, Lui MT, Cheng CY, Kao SY

Differential expression of E-cadherin in metastatic lesions comparing to primary oral squamous cell carcinoma

J Oral Pathol Med. 35:589-94, 2006

Wang IK, Yan AH, Lui MT, Wu CH, Kao SY

Dermatofibrosarcoma Protuberans of the face- case report and literature review

Chin. J Oral Maxillofac Surg. 17: 117-127, September 2006.

Lu SS, Chang KW, Liu CJ, Lee SY, Liu TY, Lin SC*

Ripe areca nut extract induced G1 phase cell arrest and senescence-associated phenotypes in normal human oral keratinocyte

Carcinogenesis 127: 1273-84

Liu CJ, Lin SC, Chen YJ, Chang KM, Chang KW*

Array-based comparative genomic hybridization to detect genome-wide changes in microdissected primary and metastatic oral carcinoma

Mol Carcinog 45:721-31

Lin SC, Liu CJ, Yeh WI, Lui MT, Chang KW*, Chang CS*

Functional polymorphism in NFKB1 promoter is related to the risks of oral squamous cell carcinoma occurring on male areca (betel) chewers

Cancer Letters 243: 47-54

Wong YK, Chang KW, Cheng CY, Liu CJ*

Association of CTLA-4 gene polymorphism with oral squamous cell carcinoma

J Oral Pathol Med 35:51-4

Chiang WC, Wong YK, Lin SC, Chang KW, Liu CJ*

Increase of MMP-13 expression in multi-stage oral carcinogenesis and epigallocatechin-3-gallate suppress MMP-13 expression

Oral Dis 12: 27-33

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項目指標  2007年


作者

論文

期刊

Yang MH, Chang SY, Chiou SH, Liu CJ, Chi CW, Chen PM, Teng SC, Wu KJ.

Overexpression of NBS1 induces epithelial-mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer.

Oncologist 2007; 12:312-9.

Tseng YH, Chang CS, Liu TY, Kao SY, Chang KW, Lin SC

Areca nut extract treatment down-regulates involucrin in normal human oral keratinocyte through P13K/AKT activation.

Oral Oncol. 43:670-679, 2007

Li YJ, Kao SY, and Chang CS

Leiomyosarcoma of cheek: a case report

Chin. J Oral Maxillofac Surg. 18:58-68, 2007.

Tu HF, Wu CH, Kao SY, Liu CJ, Liu TY, Lui MT

Functional -1562 C-to-T polymorphism in matrix metalloproteinase-9 (MMP-9) promoter is associated with the risk for oral squamous cell carcinoma in younger male areca users

J Oral Pathol Med. 2007 Aug;36(7):409-14

Chen YW, Lin JS, Fong JH, Wang IK, Chou SJ, Wu CH, Lui MT, Chang CS, Kao SY

Use of methylene blue as a diagnostic aid in early detection of oral cancer and precancerous lesions.

Br J Oral Maxillofac Surg. 45 (2007) 590-91

Chen YW, Tu Hsi-Fen, Wu TH, Lo WL, Chang CS, Chang KW, Kao SY

Sarcomas and sarcomatoid tumor after radiotherapy of oral squamous cell carcinoma: Analysis of cases

Oral Surg, Oral Med, Oral Pathol, Oral Radiol, Endod. 2007 May 14; [Epub ahead of print]

Hung PS, Kao SY, Chiou YH, Liu CJ, Chang KW, Lin SC

Insulin-like growth factor binding protein-5 (IGFBP-5) suppersses the tumourigenesis of head and neck squamous cell carcinoma

J Pathol 2007;213:000-000

Tseng YH, Chang KW, Liu CJ, Lin CY, Yang SC, Lin SC*

Areca nut extract represses migration and differentiation while activating MMP-9 of normal gingival epithelial cells

J Periodont Res(2007, In press)

Chiang WF, Liu SY, Lin CN, Yen CY, Chen YC, Lin SC, Chang KW*

Association of epidermal growth factor receptor (EGFR) gene copy number amplification with neck lymph node metastasis in areca-associated oral carcinomas

Oral Oncol(2007, In press)

Hung PS, Kao SY, Shih YH, Chiou SH, Liu CJ, Chang KW*, Lin SC*

Insulin-like growth factor binding protein-5 (IGFBP-5) suppresses the tumorigenesis of head and neck squamous cell carcinoma

J Pathol(2007, In press)

Liu CJ, Kuo LT, Cheng HW, Liu TY, Chang KW*, Lin SC*

Differential gene expression signature between primary and metastatic head and neck squamous cell carcinoma.

J Pathol(2007, In press)

Ko SY, Chang KW, Lin SC, Hsu HC, Liu TY*

The repressive effect of green tea ingredients on amyloid precursor protein (APP) expression in oral carcinoma cells in vitro and in vivo

Cancer Letters 245: 81-89

Lu CC, Chang KW,Chou FC, Cheng CY, Liu CJ*

Association of pretreatment thrombocytosis with disease progression and survival in oral squamous cell carcinoma

Oral Oncol 43: 283-8

Liu CJ, Lui MT, Chen HL, Lin SC, Chang KW*

MICA and MICB overeexpression in oral squamous cell carcinoma

J Oral Pathol Med 36: 43 – 7

Ko SY, Lin SC, Wong YK, Liu CJ, Chang KW*, Liu TY*

Increase of disintegrin metalloproteases 10 (ADAM10) expression in oral squamous cell carcinoma

Cancer Letters 245: 33-43

Tseng YH, Chang CS, Liu TY, Kao SY, Chang KW*, Lin SC*

Areca nut extract treatment down-regulates involucrin in normal human oral keratinocyte through AKT activation

Oral Oncol 43: 670-9

Shieh TM, Lin SC, Liu CJ, Chang SC, Ku TH, Chang KW*

Association of expression aberrances and genetic polymorphisms of lysyl oxidase (LOX) with areca-associated oral tumorigenesis

Clin Cancer Res 13: 4378-85

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