最新消息

氣管及食道狹窄的人有福了

漏斗胸的最新療法

168位重症肌無力病患之手術結果, 改善率超過7成

肺氣腫的手術療法

    學歷  

                                                                                 
     國立陽明大學臨床醫學研究所博士
          國立陽明醫學院 醫學士
      

  進修

         美國聖路易市華盛頓大學胸腔外科研究員
         美國南加大醫學中心胸腔外科研究員

    經歷                                                                              

         台北榮民總醫院外科部住院及總醫師
         台北榮民總醫院胸腔外科總醫師
         桃園榮民醫院外科總醫師
         桃園榮民醫院外科主治醫師
         台北榮民總醫院胸腔外科主治醫師
         國立陽明大學醫學院醫學系外科助理教授

  研究計畫

1.            Partial Liquid Ventilation for Ischemic-Reperfusion Injury after Rat Lung Transplantation. 液體Perfluorocarbon(PFC)通氣治療老鼠單肺移植後之缺血重灌注傷害(台北榮總院內計劃 91年1月-91年12月)

2.            Living-related Donor Lobectomy for Lobar Transplantation-Setup of Animal Model. 活體肺臟移植動物實驗(盧光舜肺癌基金會 91年1月-91年12月)

3.            Continuous Cyclic Ventilation of Allograft in Cold Storage for Lung Preservation. 持續通氣對肺臟保存之影響(台北榮總院內計劃 92年1月-92年12月)

4.            Two-layer Method (UW solution/Perfluorochemical plus O₂) for Lung Preservation in Rat Lung Transplantation. 雙層式保存液之運用在老鼠之單肺移植試驗(國科會計畫 91年8月-92年7月)

5.            Antegrade versus Retrograde Flush for Lung Preservation in Canine Pulmonary Transplantation. 順流與逆流灌注肺保存液對肺臟移植之影響(盧光舜肺癌基金會 92年1月-92年12月)

6.            The Effect of Cyclooxygenase-2 Inhibitor, NS-398, in Rat Lung Transplantation.  Cyclooxygenase-2 Inhibitor(NS-398)在老鼠肺臟移植之作用(台北榮總院內計劃 93年1月-93年12月)

7.            The Prognostic Significance of p53/MDM2/P14ARF Pathway in Non-small Cell Lung Cancer. 肺非小細胞癌組織中p53/MDM2/P14ARF Pathway之表現與肺癌病患預後之相關分析. (盧光舜肺癌基金會 93年1月-93年12月)

8.            Alteration of DNA Methyltransferase Expression and Its Association with DNA Methylation of CpG Islands in Human Non-small Cell Lung Cancer. 甲基轉移酵素異常及基因甲基化與肺癌之相關研究(國科會計畫 93年8月-94年7月)

9.            The Significance of hMLH1 and hMSH2 Inactivation by Promoter Methylation in Female with Non-small Cell Lung Cancer. 女性肺癌組織中hMLH1 and hMSH2 基因之表現與病患之相關意義(台北榮總院內計劃 94年1月-94年12月)

10.        Retrograde Flush in Canine Lung Transplantation with Non-heart-beating Donors. 逆流性沖洗及無心跳捐贈肺在肺臟移植之使用(台北榮總移植小組院內計劃 94年1月-94年12月)

11.        The Prognostic Significance of Preoperative CEA Serum Level in Female with Non-small Cell Lung Cancer. 術前血液CEA值與女性肺癌病患預後之相關分析(盧光舜肺癌基金會 94年1月-94年12月)

12.        Molecular Evaluation of Inhibitors of Protein Kinase B/AKT on Therapeutic Treatment of Lung Cancer. AKT抑制劑作為肺癌治療之評估及分子機轉研究(台北榮總院內計劃 95年1月-95年12月)

13.        Lung Retrieval from Non-heart-beating Donors in Rat Lung Transplantation Model. 利用無心跳捐贈肺老鼠肺臟移植模型之建立(台北榮總移植小組院內計劃 95年1月-95年12月)

14.        Relapse of Symptom After Transsternal Thymectomy for Myasthenia Gravis. 重症肌無力病患術後復發因素之研究分析(盧光舜肺癌基金會 95年1月-95年12月)

15.        Polymorphic Analysis of Mismatch Repair Genes hMLH1 and hMSH2 with Lung Cancer Susceptibility and Prognosis in Taiwan. 台灣hMLH1 及hMSH2基因多型性與肺癌罹患機率之相關研究(國科會計畫 95年8月-96年7月)

16.    The Significance of Cell Cycle Regulators CDKN2A(p16^INK4a and p14^ARF)and p53 genes in Squamous Cell Carcinoma of the Esophagus. 細胞生命週期調控基因CDKN2A(p16^INK4a 及 p14^ARF)及 p53 基因在食道癌之表現機轉探討及臨床意義(台北榮總院內計劃 96年1月-96年12月)

17.     En Bloc Resection for Lung Cancer with Chest Wall Invasion. 非小細胞肺癌合併胸壁侵犯接受廣泛整體肺合併胸壁切除的結果(盧光舜肺癌基金會 96年1月-96年12月)

1.        Han-Shui Hsu, Ming-Sheng Chern, Chung-Hua Chen, Reury-Perng Perng. Pulmonary Gangrene: A Case Report. Chin Med J(Taipei) 1995;55:476-80

2.    Han-Shui Hsu, Liang-Shun Wang, Yu-Chung Wu, Huei-Jyh Fahn, Min-Hsiung Huang. Management of Primary Chest Wall Tuberculosis. Scand J Thor Cardiovasc Surg 1995;29:119-23(SCI)

3.    Han-Shui Hsu, Wen-Hu Hsu, Biing-Shing Huang and Min-Hsiung Huang. Surgical Treatment of Endobronchial Tuberculosis. Scand Cardiovasc J 1997;31: 79-82(SCI)

4.    Yuh-Liang Fu, Huei-Ju Fahn, Han-Shui Hsu, Yu-Chung Wu, Ming-Hsiung Huang, Liang-Shun Wang. Mangement of Descending Necrotizing Mediastinitis. Chin Med J(Taipei) 1998;61:513-9

5.    Chien-Ying Wang, Chih-Cheng Hsieh, Han-Shui Hsu, Yu-Chung Wu, Wen-Hu Hsu, Biing Shiun Huang, Tzu-Chen Lin, Min-Hsiung Huang. Pulmonary Resection for Metastases from Colorectal Adenocarcinomas. Chin Med J(Taipei) 2002;65:15-22

6.   Han-Shui Hsu, Chien-Ying Wang, Ming-Yin Li, Min-Hsiung Huang. Endotracheobronchial neurofibromas. Ann Thorac Surg 2002;74:1704-6(SCI)

7.    Richard J. Battafarano, Jay F. Piccirillo, Bryan F. Meyers, Han-Shui Hsu, Tracey J. Guthrie, Joel D. Cooper, and G. Alexander Patterson. Impact of comorbidity on survival after surgical resection in patients with stage I non–small cell lung cancer. J Thorac Cardiovasc Surg 2002;123: 280-287(SCI)

8.    Chien-Ho Tsai, Han-Shui Hsu, Liang-Shung Wang, Hao-Wei Wang,Yu-Chung Wu, Chih-Cheng Hsieh, Biing-Shiun Huang, Wen-Hu Hsu, Min-Hsiung Huang. Surgical results of squamous cell carcinoma of the esophagus in young patients. Chin Med(Taipei) 2003;66:288-93

9.    Han-Shui Hsu, Liang-Shung Wang, Chih-Cheng Hsieh, Yu-Chung Wu, Biing-Shiun Huang, Wen-Hu Hsu, Min-Hsiung Huang. The role of mediastinoscopy in the evaluation of thoracic disease and lung cancer. Chin Med J(Taipei) 2003;66:231-5

10.  Chien-Sheng Huang, Han-Shui Hsu, Ko-Pei Kao, Min-Hsiung Huang, Biing-Shiun Huang. Intravenous immunoglobulin in the preparation of thymectomy for myasthenia gravis. Acta Neurol Scand 2003;108:136-8(SCI)

11.  Han-shui Hsu, Chien-Ying Wang, Chih-Cheng Hsieh, Min-Hsiung Huang. Short-segment Colon Interposition for End-stage Achalasia. Ann Thorac Surg 2003;76:1706-10.(SCI)

12.  Yung-Chang Lien, Han-Shui Hsu, Wing-Yin Li, Yu-Chung Wu, Wen-Hu Hsu, Liang-Shun Wang, Min-Hsiung Huang, Biing-Shiun Huang. Pulmonary Harmatoma. Chin Med J(Taipei) 2004;67:21-6

13.  Chen-Sung Lin, Kuang-Tai Kuo, Wen-Hu Hsu, Biing-Shiun Huang, Yu-Chung Wu, Han-Shui Hsu, Min-Hsiung Huang, Liang-Shun Wang. Managements of locally advanced unresectable thymic epithelial tumors. J Chin Med Assoc 2004;67:172-8

14.  Chen-Sung Lin, Han-Shui Hsu, Chien-Ho Tsai, Wing-Yin Li, Min-Hsiung Huang. Gastric schwannoma. J Chin Med Assoc 2004;67:583-6

15.  Han-Shui Hsu, Yu-Chien Wang, Ruo-Chia Tseng, Jer-Wei Chang, Jung-Ta Chen, Chuen-Ming Shih, Chih-Yi Chen, and Yi-Ching Wang. 5’CpG hypermethylation Is Responsible for p14ARF Inactivation and Inversely Correlates with p53 Overexpression in resected non-small cell lung cancer. Clinical Cancer Research 2004;10:4734-41(SCI)

16.  Yung-Chang Lien, Chih-Cheng Hsieh, Yu-Chung Wu, Han-Shui Hsu, Wen-Hu Hsu, Liang-Shun Wang, Min-Hsiung Huang, Biing-Shiun Huang. Preoperative serum albumin level is a prognostic indicator for adenocarcinoma of the gastric cardia. J Gastrointest Surg 2004;8:1041-8(SCI)

17.  Yo-Ju Chen, Han-Shui Hsu, Chih-Cheng Hsieh, Yu-Chung Wu, Liang-Shun Wang, Wen-Hu, Hsu, Min-Hsiung Huang, Biing-Shiun Huang. Pulmonary metastasectomy for hepatocellular carcinoma. J Chin Med Assoc 2004;67:621-4

18.   Chien-Ying Wang, Han-Shui Hsu, Yu-Chung Wu, Min-Hsiung Haung, Wen-Hu Hsu. Intramural lipoma of the esophagus. J Chin Med Assoc 2005;68:240-3

19.  Han-Shui Hsu, Min-Hsiung Huang. Surgical therapy for end-stage achalasia. Reply to the Editor. Ann Thorac Surg 2005;79:749-50(SCI)

20.  Chien-Sheng Huang, MD, Han-Shui Hsu, MD, Biing-Shiun Huang, MD, PhD, Ko-Pei Kao, MD, Wen-Hu Hsu, MD, Min-Hsiung Huang, MD. Factors Influencing the Outcome of Transsternal Thymectomy for Myasthenia Gravis. Acta Neurologica Scandinavica 2005;112:108-14 ( Correspondence Author) (SCI)

21.  Han-Shui Hsu, Chiao-Kai Wen, Yen-An Tang, Ruo-Kai Lin, Wing-Yin Li, Wen-Hu Hsu, Yi-Ching Wang. Promoter hypermethylation is the predominant mechanism in hMLH1 and hMSH2 deregulation and is a poor prognostic factor in non-smoking lung cancer. Clin Cancer Res 2005;11:5410-6(SCI)

22.  Ming-Jer Huang, Ken-Hong Lim, Chin-Yuan Tzen, Han-Shui Hsu, Yun Yen, Biing-Shiun Huang. EGFR mutations in malignant pleural effusion of non-small cell lung cancer: A case report. Lung Cancer 2005;49:413-5(SCI)

23.   Ching Tzao, Han-Shui Hsu, Guang-Huan Sun, Hsiou-Lei Lai, Yi-Ching Wang, Ho-Jui Tung, Cheng-Ping Yu, Yeung-Leung Cheng, Shih-Chun Lee. Promoter methylation of the hMLH1 gene and protein expression of human mutL homolog 1 and human mutS homolog 2 in resected esophageal squamous cell carcinoma. J Thorac Cardiovasc Surg 2005;130:1371-7(SCI)

24.  Han-Shui Hsu, MD, Chien-Sheng Huang, MD, Biing-Shiun Huang, MD, PhD, Hui-Chen Lee, BA, Ko-Pei Kao, MD, Wen-Hu Hsu, MD, Min-Hsiung Huang, MD. Thymoma Is Associated with Relapse of Symptoms after Transsternal Thymectomy for Myasthenia Gravis. Interactive CardioVascular and Thoracic Surgery 2006;5:42-6

25. Po-Kuei Hsu, Han-Shui Hsu, Anna Fen-Yau Li, Liang-Shun Wang, Biing-Shiun Huang, Min-Hsiung Huang, Wen-Hu Hsu. Non-Hodgkin’s lymphoma presenting as a large chest wall mass. Ann Thorac Surg 2006;81:1214-9 ( Correspondence Author) (SCI)

26.  Yu-Teng Lin, Po-Kuei Hsu, Han-Shui Hsu, Chien-Sheng Huang, Liang-Shun Wang, Biing-Shiun Huang, Wen-Hu Hsu, Min-Hsiung Huang. En Bloc resection for lung cancer with chest wall invasion. J Clin Med Assoc 2006;69:157-161( Correspondence Author)

27.  Ching Tzao, Guang-Huan Sun, Ho-Jui Tung, Han-Shui Hsu, Wen-Hu Hsu, Yi-Ching Wang, Yeung-Leung Cheng, Shih-Chun Lee. Reduced acetylated histone H4 is associated with promoter methylation of the fragile histidine triad gene in resected esophageal squamous cell carcinoma. Ann Thorac Surg 2006;82:396-401

28.  Po-Kuei Hsu, Han-Shui Hsu, Hui-Chen Lee, Chih-Cheng Hsieh, Yu-Chung Wu, Liang-Shun Wang, Biing-Shiun Huang, Wen-Hu Hsu, Min-Hsiung Huang. Management of primary chest wall tumors: 14 years’ clinical experience. J Clin Med Assoc 2006;69:377-82( Correspondence Author)

29. Yi-Ching Wang, Han-Shui Hsu, Tsz-Pei Chen, Jung-Ta Chen. Molecular diagnostic markers for lung cancer in sputum and plasma. Ann NY Acad Sci 2006;1075:179-84(SCI)

38. Chen-Chi Liu, Po-Kuei Hsu, Wen-Chieh Huang, Min-Hsiung Huang, Han-Shui Hsu. Two-layer Method (UW solution/Perfluorochemical plus O₂) for Lung Preservation in Rat Lung Transplantation. Transplantation Proceedings, in press( Correspondence Author) (SCI)

39.   Tsz-Pei Chen, Han-Shui Hsu, Chien-Hui Hung, Jung-Ta Chen, Yi-Ching Wang. Multiple genetic and epigenetic biomarkers for lung cancer detection in cytologically negative sputum and a nested case-control study for risk assessment. Journal of Pathology, in revision(SCI)