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陳燕彰 (Yann- Jang Chen)


  • 學歷
    • 國立陽明交通大學 微生物免疫研究所 博士
    • 國立陽明交通大學醫學院 傳學研究所 碩士
    • 國立陽明交通大學醫學院 醫學系 學士
  • 經歷
    • - 迄今 臺北榮民總醫院 遺傳諮詢中心 主任
    • - 迄今 臺北榮民總醫院 兒童遺傳內分泌科 主治醫師
    • - 迄今 國立陽明交通大學 生命科學系暨基因體科學研究所 副教授
    • - 迄今 國立陽明交通大學 臨床醫學研究所 副教授
    • - 台北市立聯合醫院 醫學研究中心 研究主治醫師
    • - 台北市立聯合醫院仁愛院區 小兒科 主治醫師
    • - 台北市立聯合醫院 人體生物資料庫 副召集人
    • - 台北市立聯合醫院 人體試驗委員會 執行秘書
    • - 台北市立聯合醫院 人體試驗委員會 副主委
    • - 國立陽明大學 通識教育中心 副教授
    • - 美國加州大學柏克萊分校 勞倫斯國家實驗室 訪問學者
  • 醫療專長
    1. 一般兒科
    2. 醫學遺傳學
    3. 腫瘤基因體學
    4. 染色體與基因異常分析
    5. 兒童新陳代謝學
    6. 兒童生長發育與性早熟


Chen JE, Chen YR, Wang HH, Niu DM, Cheng YF, Chen YJ. KMT2D-related disorder with a restricted spectrum distinct from Kabuki syndrome: A rare case report describing male twins in Taiwan and a literature review Pediatr Neonatol. 2022 Jul 31:S1875-9572(22)00157-7.

Yang MH, Chen JW, Wei ST, Hou SM, Chen YJ. The efficacy of ethnic specific blood groups genotyping for routine donor investigation and rare donor identification in Taiwan. Vox Sang. 2022 Jan;117(1):99-108. doi: 10.1111/vox.13133..

Yang MH, Chen JW, Sayaka K, Uchikawa M, Tsuno NH, Wei ST, Hou SM, Chen YJ. Universal Detection of Mia Antigen and Frequencies of Glycophorin Hybrids among Blood Donors in Taiwan by Human Monoclonal Antibodies against Mia (MNS7), Mur (MNS10), and MUT (MNS35) Antigens. Diagnostics (Basel). 2021 Apr 29;11(5):806. doi: 10.3390/diagnostics11050806. PMID: 33946749; PMCID: PMC8146793.

Liang Y, Wang ML, Chien CS, Yarmishyn AA, Yang YP, Lai WY, Luo YH, Lin YT, Chen YJ, Chang PC, Chiou SH. (2020, May). Highlight of Immune Pathogenic Response and Hematopathologic Effect in SARS-CoV, MERS-CoV, and SARS-Cov-2 Infection. Frontiers in Immunology, 11:1022.

Lin CH, Wang HH, Chen TH, Chiang MC, Hung PH, Chen YJ. (2020, Apr). Involvement of MicroRNA-296 in the Inhibitory Effect of Epigallocatechin Gallate against the Migratory Properties of Anoikis-Resistant Nasopharyngeal Carcinoma Cells. Cancers, 12(4):973.

Hsuan-Chieh Liao, Chien-Hui Liao, Shu-Min Kao, Chuan-Chi Chiang, and Yann-Jang Chen (2019, Jan). Detecting 22q11.2 Deletion Syndrome in Newborns with Low T Cell Receptor Excision Circles from Severe Combined Immunodeficiency Screening. Journal of Pediatrics, 204:219-224.

Lee CL, Lin HY, Chuang CK, Chiu HC, Tu RY, Huang YH, Hwu WL, Tsai FJ, Chiu PC, Niu DM, Chen YJ, Chao MC, Chang TM, Lin JL, Chang CY, Kao YC, Lin SP. Functional independence of Taiwanese patients with mucopolysaccharidoses. Mol Genet Genomic Med. 2019 Aug;7(8):e790.

Hsieh CC, Hsu HS, Li AF, Chen YJ. (2018, Jul). Clinical relevance of PD-L1 and PD-L2 overexpression in patients with esophageal squamous cell carcinoma.. Journal of Thoracic Disease, 10(7):4433-4444.

CH LIN, MC Chiang, YJ Chen (2018, Apr). MicroRNA-328 inhibits migration and epithelial-mesenchymal transition by targeting CD44 in nasopharyngeal carcinoma cells.. OncoTargets and Therapy, 11:2375-2385.

Liao HC, Hsu TR, Young L, Chiang CC, Huang CK, Liu HC, Niu DM, Chen YJ (2018, Feb). Functional and biological studies of α-galactosidase A variants with uncertain significance from newborn screening in Taiwan. Molecular Genetics and Metabolism, 123(2):140-147.

Lin CH, Chiang MC, Chen YJ. STAT3 mediates resistance to anoikis and promotes invasiveness of nasopharyngeal cancer cells. Int J Mol Med. 2017 Nov;40(5):1549-1556.

Hsieh CC, Hsu HS, Chang SC, Chen YJ. Circulating Cell-Free DNA Levels Could Predict Oncological Outcomes of Patients Undergoing Esophagectomy for Esophageal Squamous Cell Carcinoma. Int J Mol Sci. 2016 Dec 17;17(12). pii: E2131

Shen YA, Wang CY, Chuang HY, Hwang JJ, Chi WH, Shu CH, Ho CY, Li WY, Chen YJ. CD44 and CD24 coordinate the reprogramming of nasopharyngeal carcinoma cells towards a cancer stem cell phenotype through STAT3 activation. Oncotarget 2016. 7(36):58351-58366

Shen YA, Wang CY, Hsieh YT, Chen YJ, and Wei YH. Metabolic reprogramming orchestrates cancer stem cell properties in nasopharyngeal carcinoma. Cell Cycle 2015;14(1):86-98