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陳倩 (Chien Chen)


  • 經歷
    • - 迄今 台北榮民總醫院主治醫師
    • - 迄今 國立陽明大學醫學院講師
    • - 迄今 亞太癲癇學院秘書
    • - 迄今 伊比力斯協會秘書長
  • 醫療專長
    1. 癲癇症之治療
    2. 腦電波
    3. 癲癇手術之術前評估
    4. 兒童癲癇



1. Clinical management of epilepsy

2. Pre-surgical evaluations for epilepsy

3. Study of malformation of cortical development

4. Study of EEG electrophysiology

Awards and Honors

2015國家生技醫療品質獎【特色醫療組銅獎】: 北榮癲癇外科手術多領域治療團隊

Selected Publications

  1. Chen C, Yen DJ, Yiu CH, Shih YH, Yu HY, Su MS. Ictal vomiting in partial seizures of temporal lobe origin. Eur Neurol 1999; 42: 235-239.
  2. Lin KN, Teng EL, Wang PN, Chuang YY, Chen C, Liu CY, Liu HC. Patients’ versus caregivers’ report of poor memory in relation to dementia and tested abilities. Neurology 2000; 55: 1758-1759.
  3. Yen DJ, Yu HY, Guo YC, Chen C, Yiu CH, Su MS. A double-blind, placebo-controlled study of Topiramate in adult patients with refractory partial epilepsy. Epilepsia 2000; 41: 1162-1166.
  4. Yen DJ, Chen C, Shih YH, Guo YC, Liu LT, Yu HY, Kwan SY, Yiu CH. Antiepileptic drug withdrawal in patients with temporal lobe epilepsy undergoing presurgical video-EEG monitoring. Epilepsia 2001; 42: 251-255.
  5. Yu HY, Yiu CH, Yen DJ, Chen C, Guo YC, Kwan SY, Lin YY, Shih YH. Lateralizing value of early head turning and ictal dystonia in temporal lobe seizures: a video-EEG study. Seizure 2001; 10: 428-432.
  6. Lin KN, Wang PN, Chen C, Chiu YH, Kuo CC, Chuang YY, Liu HC. The three-item clock-drawing test: a simplified screening test for Alzheimer’s disease: Eur Neurol 2003; 49: 53-58.    
  7. Chen C, Shih YH, Yen DJ, Lirng JF, Guo YC, Yu HY, Yiu CH. Olfactory auras in patients with temporal lobe epilepsy. Epilepsia 2003; 44(2): 257-260.
  8. Tsai CP, Yuan CL, Yu HY, Chen C, Guo YC, Shan DE. Multiple sclerosis in Taiwan. J Chin Med Assoc 2004; 67:500-505.
  9. Yen DJ, Lirng JF, Shih YH, Shan IK, Su TP, Chen C, Yu HY, Yiu CH. Selective posterior cerebral artery amobarbital test in patients with temporal lobe epilepsy for surgical treatment. Seizure 2006; 15: 117-124.
  10. Lai TH, Chen C, Yen DJ, Yu HY, Yiu CH, Kwan SY. Isolated acute hearing loss as the presenting symptom of leptomeningeal carcinomatosis. J Chin Med Assoc 2006; 69(10): 496-498.
  11. Wang SJ, Fuh JL, Huang SY, Yang SS, Wu ZA, Hsu CH, Wang CH, Yu HY, Wang PJ; Taiwan MAP Study Group. Diagnosis and Development of Screening Items for Migraine in Neurological Practice in Taiwan. J Formos Med Assoc. 2008; 107(6): 485-94.
  12. Yen DJ, Chung WY, Shih YH, Chen C, Lirng JF, Yiu CH, Yu HY, Su TP, Pan DH. Gamma knife radiosurgery for the treatment of recurrent seizures after incomplete anterior temporal lobectomy. Seizure. 2009; 18(7): 511-514.
  13. Yu HY, Shih YH, Su TP, Lin KN, Yiu CH, Lin YY, Kwan SY, Chen C, Yen DJ. Preoperative IQ predicts seizure outcomes after anterior temporal lobectomy. Seizure. 2009; 18(9): 639-43.
  14. Yu HY, Shih YH, Su TP, Shan IK, Yiu CH, Lin YY, Kwan SY, Chen C, Yen DJ. The Wada memory test and prediction of outcome after anterior temporal lobectomy. J Clin Neurosci. 2010; 17(7): 857-61.
  15. Yu HY, Yen DJ, Yiu CH, Lin YY, Kwan SY, Chen C, Hsu SP, Shih YH. Postoperative interictal epileptiform discharge within 1 month is associated with seizure recurrence after anterior temporal lobectomy. Epilepsy Behav. 2010; 19(3): 436-40.
  16. Lin JH, Shyu HY, Chen C, Kwan SY, Wong TT, Chang KP, Yiu CH. Reflex absence epilepsy induced by gait. Epilepsy Behav. 2011; 22(2): 395-7.
  17. Kuan YC, Yen DJ, Yiu CH, Lin YY, Kwan SY, Chen C, Chou CC, Yu HY. Treatment-seeking behavior of people with epilepsy in Taiwan: A preliminary study. Epilepsy Behav. 2011; 22(2): 308-12.
  18. Shyu HY, Lin JH, Chen C, Kwan SY, Yiu CH. An atypical case of Lennox-Gastaut syndrome not associated with mental retardation: A nosological issue. Seizure 2011; 20(10): 820-3.
  19. Lin JH, Chen C, Shyu HY, Kwan SY, Yiu CH. Stimulus-induced rhythmic, periodic, or ictal discharges - A case report. Clin Neurol Neurosurg. 2012; 114(9): 1283-6.
  20. Lee YC, Lee MJ, Yu HY, Chen C, Hsu CH, Lin KP, Liao KK, Chang MH, Liao YC, Soong BW. PRRT2 Mutations in Paroxysmal Kinesigenic Dyskinesia with Infantile Convulsions in a Taiwanese Cohort. PLoS One 2012; 7(8): e38543.
  21. Kuan YC, Shih YH, Chen C, Yu HY, Yiu CH, Lin YY, Kwan SY, Yen DJ. Abdominal auras in patients with mesial temporal sclerosis. Epilepsy Behav. 2012; 25(3): 386-90.
  22. Wang WH, Yu HY, Yen DJ, Lin YY, Kwan SY, Chen C, Hua MS. The Social and Occupational Functioning Scale for Epilepsy (SOFSE): a brief measure of functional status in a Taiwanese sample with epilepsy. Epilepsia 2013; 54(5): 888-97.
  23. Yang TF, Chen HH, Liang ML, Chen C, Chiu JW, Wang JC, Lai CJ, Liao KK, Chan RC. Intraoperative brain mapping to identify corticospinal projections during resective epilepsy surgery in children with congenital hemiparesis. Childs Nerv Syst. 2014; 30(9):1559-64.
  24. Chen HH, Chen C, Hung SC, Liang SY, Lin SC, Hsu TR, Yeh TC, Yu HY, Lin CF, Hsu SP, Liang ML, Yang TF, Chu LS, Lin YY, Chang KP, Kwan SY, Ho DM, Wong TT, Shih YH. Cognitive and epilepsy outcomes after epilepsy surgery caused by focal cortical dysplasia in children: early intervention maybe better. Childs Nerv Syst. 2014; 30(11):1885-95.
  25. Wang WH, Shih YH, Yu HY, Yen DJ, Lin YY, Kwan SY, Chen C, Hua MS. Theory of mind and social functioning in patients with temporal lobe epilepsy. Epilepsia 2015; 56(7): 1117-23. 
  26. Hsiao FJ, Yu HY, Chen WT, Kwan SY, Chen C, Yen DJ, Yiu CH, Shih YH, Lin YY. Increased Intrinsic Connectivity of the Default Mode Network in Temporal Lobe Epilepsy: Evidence from Resting-State MEG Recordings. PLoS One 2015; 10(6): e0128787.
  27. Liu YT, Nian FS, Chou WJ, Tai CY, Kwan SY, Chen C, Kuo PW, Lin PH, Chen CY, Huang CW, Lee YC, Soong BW, Tsai JW. PRRT2 mutations lead to neuronal dysfunction and neurodevelopmental defects. Oncotarget. 2016; 7(26): 39184-39196.
  28. Chen-Wei Chou, Chien Chen, Shang-Yeong Kwan, Shun-Chi Wu. Multi-channel algorithms for epileptic high-frequency oscillation detection. Conf Proc IEEE Eng Med Biol Soc. 2016; 2016: 948-951.
  29. Hung PL, Huang LT, Kwan SY, Chang KP, Chen HH, Lee YY, Fan HC, Chen C. Ictus emeticus presenting as an unusual seizure type in chromosome 22q11.2 deletion syndrome. Epileptic Disord. 2017; 19(1): 76-81. (corresponding author)
  30. Yang CY, Chen HH, Chen C, Chiu JW, Chou CL, Yang TF. Pattern of Corticospinal Projections Defined by Brain Mapping During Resective Epilepsy Surgery in a Patient with Congenital Hemiparesis and Intractable Epilepsy. World Neurosurg. 2017; (17): 31372-4.
  31. Yu HY, Hsu SPC, Lin CF, Shih YH, Yen DJ, Kwan SY, Chen C, Chou CC. Prognostic significance of postoperative spikes varied in different surgical procedures for mesial temporal sclerosis. Seizure. 2017: 52:71-75.
  32. Lu IL, Chen C, Tung CY, Chen HH, Pan JP, Chang CH, Cheng JS, Chen YA, Wang CH, Huang CW, Kang YN, Chang HY, Li LL, Chang KP, Shih YH, Lin CH, Kwan SY, Tsai JW. Identification of genes associated with cortical malformation using a transposon-mediated somatic mutagenesis screen in mice. Nat Commun. 2018; 9(1): 2498.
  33. Peng SJ, Chou CC, Yu HY, Chen C, Yen DJ, Kwan SY, Hsu SPC, Lin CF, Chen HH, Lee CC. Ictal networks of temporal lobe epilepsy: views from high-frequency oscillations in stereoelectroencephalography. J Neurosurg. 2018; 1: 1-9.
  34. Su YC, Wu SC, Chen C, Chou CW, Hung SC, Lee Swindlehurst A, Kwan SY. Sample Entropy of High Frequency Oscillations for Epileptogenic Zone Localization. Conf Proc IEEE Eng Med Biol Soc. 2018; 7: 1-4.
  35. Peng SJ, Chou CC, Yu HY, Chen C, Yen DJ, Kwan SY, Hsu SPC, Lin CF, Chen HH, Lee CC. Ictal networks of temporal lobe epilepsy: views from high-frequency oscillations in stereoelectroencephalography. J Neurosurg. 2018; 1:1-9.
  36. Hung SC, Lee CC, Chen HH, Chen C, Wu HM, Lin CP, Peng SJ. Early recovery of interhemispheric functional connectivity after corpus callosotomy. Epilepsia. 2019; 60(6): 1126-1136.
  37. Chou CC, Lee CC, Lin CF, Chen YH, Peng SJ, Hsiao FJ, Yu HY, Chen C, Chen HH, Shih YH. Cingulate gyrus epilepsy: semiology, invasive EEG, and surgical approaches. .Neurosurg Focus. 2020 Apr 1; 48(4): E8.
  38. Hung PL, JL, Chen C, Hung KY, Hsieh TY, Hsu MH, Kuo HC and Lin YJ. An Examination of Serum Acylcarnitine and Amino Acid Profiles at Different Time Point of Ketogenic Diet Therapy and Their Association of Ketogenic Diet Effectiveness. Nutrients. 2021; 13: 21.
  39. Yu HY, Lin CF, Chou CC, Lu YJ, Hsu SPC, Lee CC, Chen C. Outcomes of hippocampus-sparing lesionectomy for temporal lobe epilepsy and the significance of intraoperative hippocampography. Clin Neurophysiol. 2021;132(3): 746-755.
  40. Chou CC, Lin PT, Yen DJ, Yu HY, Kwan SY, Chen C, Liu YT, Shih YC, Lin SY. Acute withdrawal of new-generation antiepileptic drugs in epilepsy monitoring units: Safety and efficacy. Epilepsy Behav. 2021; 117: 107846. 
  41. Yu WY, Low I, Chen C, Fuh JL, Chen LF. Brain Dynamics Altered by Photic Stimulation in Patients with Alzheimer's Disease and Mild Cognitive Impairment. Entropy (Basel). 2021; 23(4): 427. 
  42. Su TY, Hung PL, Chen C, Lin YJ, Peng SJ. Graph Theory-BasedElectroencephalographic Connectivity and Its Association with Ketogenic Diet Effectiveness in Epileptic Children. Nutrients. 2021; 13(7): 2186.