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Yo-Tsen Liu (劉祐岑)

Yo-Tsen Liu(劉祐岑)

簡介

學歷
  1. 臺灣大學醫學系畢業
  2. 英國倫敦學院大學神經學研究所(UCL Institute of Neurology, Queen Square, London, U.K.)博士
經歷 現職: - 迄今 臺北榮總神經內科癲癇科之主治醫師
醫療專長
  1. 癲癇
  2. 巴金森氏症
  3. 動作障礙疾病
  4. 神經遺傳疾病

著作

臺灣大學醫學系畢業,英國倫敦學院大學神經學研究所(UCL Institute of Neurology, Queen Square, London, U.K.)博士,現為臺北榮總神經內科癲癇科之主治醫師。臨床和學術專長為癲癇、睡眠障礙、慢性疼痛、不自主運動及動作障礙、以及神經疾病之基因診斷。

得獎紀錄:
國立陽明大學醫學院107學年、106學年、105學年優良教師(連續三年)
國立陽明大學醫學系107學年、106年、105年PBL引導老師優良教師
台北榮民總醫院PGY票選優良教學醫師
108年第15屆榮總台灣聯合大學合作研究計畫『優良壁報論文』第一名
台灣動作障礙學會106年年會優秀論文
台灣癲癇醫學會106年研究論文獎第一名


台北榮總癲癇及相關疾病基因檢測服務(檔案連結: https://goo.gl/dj1C3m)
1. 檢測疾病: Epilepsy、Episodic ataxia、Glucose transport protein type deficiency syndrome (GLUT1-DS)、Paroxysmal kinesgenic dyskinesia (PKD)、Neurofibromatosis、Tuberous Sclerosis Complex、Wilson disease等。
2. 檢測基因: ATP7B、TSC1、TSC2、NF1、NF2、SLC2A1、SCN1A等。
3. 聯絡方式: 請於週一至週五上午9:00-12:00或下午1:30-5:30聯絡台北榮總神經內科腦波室蔡護理師 或 陳護理師 (02-2875-7580轉7580)。

1.   PDXK mutations cause polyneuropathy responsive to PLP supplementation. Chelban V, Liu YT, Houlden H*, et al ; Care4Rare Canada Consortium; SYNaPS Study Group. Ann Neurol. 2019 Jun 11. (SCI)

2.   Clinical and genetic profiles of hereditary transthyretin amyloidosis in Taiwan. Chao HC, Liao YC, Liu YT, Guo YC, Chang FP, Lee YC*, Lin KP*. Annals of Clinical and Translational Neurology, accepted on March 19, 2019. (SCI)

3.   PRRT2 Missense Mutations Cluster near C-terminus and Frequently Lead to Protein Mislocalization. Tsai MH, Nian FS, Hsu MH, Liu WS, Liu YT, Liu C, Lin PH, Hwang DY, Chuang YC, Tsai JW. Epilepsia. 2019 May;60(5):807-817. (SCI)

4.   Contributions of Animal Models to the Mechanisms and Therapies of Transthyretin Amyloidosis. Ibrahim RB, Liu YT, Yeh SY, Tsai JW. Front Physiol. 2019 Apr 2;10:338. doi: 10.3389/fphys.2019.00338. eCollection 2019. Review. (SCI)

5.   Aberrant sensory gating of the primary somatosensory cortex contributes to the motor circuit dysfunction in paroxysmal kinesigenic dyskinesia. Liu YT, Chen YC, Kwan SY, Chou CC, Yu HY, Yen DJ, Liao KK, Chen WT, Lin YY, Chen RS, Jih KY, Lu SF, Wu YT, Wang PS, Hsiao FJ*. Front Neurol. 2018 Oct 15;9:831. (SCI)

6.   Clinical and Biophysical Characterization of Nineteen GJB1 Mutations. Tsai PC, Yang DM, Liao YC, Chiu YU, Kuo HC, Su YP, Guo YC, Soong BW, Lin KP, Liu YT*(Co-corresponding Author), Lee YC*. Ann Clin Transl Neurol. 2016 Sep 1;3(11):854-865.

7.   PRRT2 mutations lead to neuronal dysfunction and neurodevelopmental defects. Liu YT, Nian FS, Chou WJ, Tai CY, Kwan SY, Chen C, Kuo PW, Lin PH, Chen CY, Lee YC, Soong BW*, Tsai JW*. Oncotarget. 2016 Jun 28;7(26):39184-39196. (SCI)

8.   What we have learned from the next generation sequencing: contributions to the genetic diagnoses and understanding of pathomechanisms of neurodegenerative diseases. Liu YT, Lee YC, Soong BW. J Neurogenet. 2015 Jun-Sep;29(2-3):103-12.

9.   Defects of mutant DNMT1 are linked to a spectrum of neurological disorders. Baets J, Duan X, Wu Y, Smith G, Seeley W, Mademan I, McGrath NM, Beade NC, Khoury J, Botuyan M, Mer G, Worrell GA, Hojo K, DeLeon J, Laura M, Liu YT, Senderek JP, Weis J, Van den Bergh P, Merrill SL, Reilly MM, Houlden H, Grossman M, Scherer S, De Jonghe P, Dyck PJ, Klein CJ. Brain. 2015 Apr;138(Pt 4):845-61.

10.       Extended phenotypic spectrum of KIF5A mutations: from spastic paraplegia to axonal neuropathy. Liu YT, Laurá M, Hersheson J, Horga A, Jaunmuktane Z, Brandner S, Pittman A, Hughes D, Polke J, Sweeney MG, Proukakis C,  Janssen JC, Auer-Grumbach M, Zuchner S, Shields K, Reilly MM, and Houlden H. Neurology. 2014 Jul 9;83(1):1-8.

11.       Autosomal-recessive cerebellar ataxia caused by a novel ADCK3 mutation that elongates the protein: clinical, genetic and biochemical characterisation. Liu YT, Hersheson J, Plagnol V, Fawcett K, Duberley KE, Preza E, Hargreaves IP, Chalasani A, Laurá M, Wood NW, Reilly MM, Houlden H. J Neurol Neurosurg Psychiatry. 2014 May;85(5):493-8.

12.       Novel C12orf65 mutations in patients with axonal neuropathy and optic atrophy. Tucci A, Liu YT, Preza E, Pitceathly RD, Chalasani A, Plagnol V, Land JM, Trabzuni D, Ryten M; on behalf of UKBEC, Jaunmuktane Z, Reilly MM, Brandner S, Hargreaves I, Hardy J, Singleton AB, Abramov AY, Houlden H. J Neurol Neurosurg Psychiatry. 2014 May;85(5):486-92. (SCI)